Drug capture materials based on genomic DNA-functionalized magnetic nanoparticles
Chemotherapy agents are prone to producing severe side-effects, and their sequestration prior to their entering of the circulatory system is thus highly desirable. Here, the authors functionalize iron oxide nanoparticles with genomic DNA and achieve sequestration of doxorubicin, cisplatin, and epiru...
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Nature Portfolio
2018
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oai:doaj.org-article:23ea153931824599ac2105f9ce1a046a2021-12-02T17:33:05ZDrug capture materials based on genomic DNA-functionalized magnetic nanoparticles10.1038/s41467-018-05305-22041-1723https://doaj.org/article/23ea153931824599ac2105f9ce1a046a2018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05305-2https://doaj.org/toc/2041-1723Chemotherapy agents are prone to producing severe side-effects, and their sequestration prior to their entering of the circulatory system is thus highly desirable. Here, the authors functionalize iron oxide nanoparticles with genomic DNA and achieve sequestration of doxorubicin, cisplatin, and epirubicin from biological solutions.Carl M. BlumenfeldMichael D. SchulzMariam S. AboianMark W. WilsonTerilynn MooreSteven W. HettsRobert H. GrubbsNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-7 (2018) |
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EN |
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Science Q |
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Science Q Carl M. Blumenfeld Michael D. Schulz Mariam S. Aboian Mark W. Wilson Terilynn Moore Steven W. Hetts Robert H. Grubbs Drug capture materials based on genomic DNA-functionalized magnetic nanoparticles |
description |
Chemotherapy agents are prone to producing severe side-effects, and their sequestration prior to their entering of the circulatory system is thus highly desirable. Here, the authors functionalize iron oxide nanoparticles with genomic DNA and achieve sequestration of doxorubicin, cisplatin, and epirubicin from biological solutions. |
format |
article |
author |
Carl M. Blumenfeld Michael D. Schulz Mariam S. Aboian Mark W. Wilson Terilynn Moore Steven W. Hetts Robert H. Grubbs |
author_facet |
Carl M. Blumenfeld Michael D. Schulz Mariam S. Aboian Mark W. Wilson Terilynn Moore Steven W. Hetts Robert H. Grubbs |
author_sort |
Carl M. Blumenfeld |
title |
Drug capture materials based on genomic DNA-functionalized magnetic nanoparticles |
title_short |
Drug capture materials based on genomic DNA-functionalized magnetic nanoparticles |
title_full |
Drug capture materials based on genomic DNA-functionalized magnetic nanoparticles |
title_fullStr |
Drug capture materials based on genomic DNA-functionalized magnetic nanoparticles |
title_full_unstemmed |
Drug capture materials based on genomic DNA-functionalized magnetic nanoparticles |
title_sort |
drug capture materials based on genomic dna-functionalized magnetic nanoparticles |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/23ea153931824599ac2105f9ce1a046a |
work_keys_str_mv |
AT carlmblumenfeld drugcapturematerialsbasedongenomicdnafunctionalizedmagneticnanoparticles AT michaeldschulz drugcapturematerialsbasedongenomicdnafunctionalizedmagneticnanoparticles AT mariamsaboian drugcapturematerialsbasedongenomicdnafunctionalizedmagneticnanoparticles AT markwwilson drugcapturematerialsbasedongenomicdnafunctionalizedmagneticnanoparticles AT terilynnmoore drugcapturematerialsbasedongenomicdnafunctionalizedmagneticnanoparticles AT stevenwhetts drugcapturematerialsbasedongenomicdnafunctionalizedmagneticnanoparticles AT roberthgrubbs drugcapturematerialsbasedongenomicdnafunctionalizedmagneticnanoparticles |
_version_ |
1718380051528941568 |