Evolution of imprinting via lineage-specific insertion of retroviral promoters

Although many species-specific imprinted genes have been identified, how the evolutionary switch from biallelic to imprinted expression occurs is still unknown. Here authors find that lineage-specific ERVs active as oocyte promoters can induce de novo DNA methylation at gDMRs and imprinting.

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Autores principales:	Aaron B. Bogutz, Julie Brind’Amour, Hisato Kobayashi, Kristoffer N. Jensen, Kazuhiko Nakabayashi, Hiroo Imai, Matthew C. Lorincz, Louis Lefebvre
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/23eab72a42084803b96998d94acb4a07
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spelling	oai:doaj.org-article:23eab72a42084803b96998d94acb4a072021-12-02T17:02:19ZEvolution of imprinting via lineage-specific insertion of retroviral promoters10.1038/s41467-019-13662-92041-1723https://doaj.org/article/23eab72a42084803b96998d94acb4a072019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13662-9https://doaj.org/toc/2041-1723Although many species-specific imprinted genes have been identified, how the evolutionary switch from biallelic to imprinted expression occurs is still unknown. Here authors find that lineage-specific ERVs active as oocyte promoters can induce de novo DNA methylation at gDMRs and imprinting.Aaron B. BogutzJulie Brind’AmourHisato KobayashiKristoffer N. JensenKazuhiko NakabayashiHiroo ImaiMatthew C. LorinczLouis LefebvreNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Aaron B. Bogutz Julie Brind’Amour Hisato Kobayashi Kristoffer N. Jensen Kazuhiko Nakabayashi Hiroo Imai Matthew C. Lorincz Louis Lefebvre Evolution of imprinting via lineage-specific insertion of retroviral promoters
description	Although many species-specific imprinted genes have been identified, how the evolutionary switch from biallelic to imprinted expression occurs is still unknown. Here authors find that lineage-specific ERVs active as oocyte promoters can induce de novo DNA methylation at gDMRs and imprinting.
format	article
author	Aaron B. Bogutz Julie Brind’Amour Hisato Kobayashi Kristoffer N. Jensen Kazuhiko Nakabayashi Hiroo Imai Matthew C. Lorincz Louis Lefebvre
author_facet	Aaron B. Bogutz Julie Brind’Amour Hisato Kobayashi Kristoffer N. Jensen Kazuhiko Nakabayashi Hiroo Imai Matthew C. Lorincz Louis Lefebvre
author_sort	Aaron B. Bogutz
title	Evolution of imprinting via lineage-specific insertion of retroviral promoters
title_short	Evolution of imprinting via lineage-specific insertion of retroviral promoters
title_full	Evolution of imprinting via lineage-specific insertion of retroviral promoters
title_fullStr	Evolution of imprinting via lineage-specific insertion of retroviral promoters
title_full_unstemmed	Evolution of imprinting via lineage-specific insertion of retroviral promoters
title_sort	evolution of imprinting via lineage-specific insertion of retroviral promoters
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/23eab72a42084803b96998d94acb4a07
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Evolution of imprinting via lineage-specific insertion of retroviral promoters

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