Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development

Plasmodium growth is adapted to the reproductive cycle of mosquitoes, but underlying mechanisms are unclear. Here, Lampe et al. show that the blood-meal induced miR-276 balances the termination of the mosquito amino acid catabolism and egg development, providing nutrients for Plasmodium sporozoite d...

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Autores principales: Lena Lampe, Marius Jentzsch, Sylwia Kierszniowska, Elena A. Levashina
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/23f1a323f4ee4ef29a1a1b5a9d1e81c3
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spelling oai:doaj.org-article:23f1a323f4ee4ef29a1a1b5a9d1e81c32021-12-02T14:38:44ZMetabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development10.1038/s41467-019-13627-y2041-1723https://doaj.org/article/23f1a323f4ee4ef29a1a1b5a9d1e81c32019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13627-yhttps://doaj.org/toc/2041-1723Plasmodium growth is adapted to the reproductive cycle of mosquitoes, but underlying mechanisms are unclear. Here, Lampe et al. show that the blood-meal induced miR-276 balances the termination of the mosquito amino acid catabolism and egg development, providing nutrients for Plasmodium sporozoite development.Lena LampeMarius JentzschSylwia KierszniowskaElena A. LevashinaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Lena Lampe
Marius Jentzsch
Sylwia Kierszniowska
Elena A. Levashina
Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development
description Plasmodium growth is adapted to the reproductive cycle of mosquitoes, but underlying mechanisms are unclear. Here, Lampe et al. show that the blood-meal induced miR-276 balances the termination of the mosquito amino acid catabolism and egg development, providing nutrients for Plasmodium sporozoite development.
format article
author Lena Lampe
Marius Jentzsch
Sylwia Kierszniowska
Elena A. Levashina
author_facet Lena Lampe
Marius Jentzsch
Sylwia Kierszniowska
Elena A. Levashina
author_sort Lena Lampe
title Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development
title_short Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development
title_full Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development
title_fullStr Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development
title_full_unstemmed Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development
title_sort metabolic balancing by mir-276 shapes the mosquito reproductive cycle and plasmodium falciparum development
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/23f1a323f4ee4ef29a1a1b5a9d1e81c3
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AT sylwiakierszniowska metabolicbalancingbymir276shapesthemosquitoreproductivecycleandplasmodiumfalciparumdevelopment
AT elenaalevashina metabolicbalancingbymir276shapesthemosquitoreproductivecycleandplasmodiumfalciparumdevelopment
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