Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development
Plasmodium growth is adapted to the reproductive cycle of mosquitoes, but underlying mechanisms are unclear. Here, Lampe et al. show that the blood-meal induced miR-276 balances the termination of the mosquito amino acid catabolism and egg development, providing nutrients for Plasmodium sporozoite d...
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2019
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oai:doaj.org-article:23f1a323f4ee4ef29a1a1b5a9d1e81c32021-12-02T14:38:44ZMetabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development10.1038/s41467-019-13627-y2041-1723https://doaj.org/article/23f1a323f4ee4ef29a1a1b5a9d1e81c32019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13627-yhttps://doaj.org/toc/2041-1723Plasmodium growth is adapted to the reproductive cycle of mosquitoes, but underlying mechanisms are unclear. Here, Lampe et al. show that the blood-meal induced miR-276 balances the termination of the mosquito amino acid catabolism and egg development, providing nutrients for Plasmodium sporozoite development.Lena LampeMarius JentzschSylwia KierszniowskaElena A. LevashinaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019) |
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Science Q Lena Lampe Marius Jentzsch Sylwia Kierszniowska Elena A. Levashina Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development |
description |
Plasmodium growth is adapted to the reproductive cycle of mosquitoes, but underlying mechanisms are unclear. Here, Lampe et al. show that the blood-meal induced miR-276 balances the termination of the mosquito amino acid catabolism and egg development, providing nutrients for Plasmodium sporozoite development. |
format |
article |
author |
Lena Lampe Marius Jentzsch Sylwia Kierszniowska Elena A. Levashina |
author_facet |
Lena Lampe Marius Jentzsch Sylwia Kierszniowska Elena A. Levashina |
author_sort |
Lena Lampe |
title |
Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development |
title_short |
Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development |
title_full |
Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development |
title_fullStr |
Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development |
title_full_unstemmed |
Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development |
title_sort |
metabolic balancing by mir-276 shapes the mosquito reproductive cycle and plasmodium falciparum development |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/23f1a323f4ee4ef29a1a1b5a9d1e81c3 |
work_keys_str_mv |
AT lenalampe metabolicbalancingbymir276shapesthemosquitoreproductivecycleandplasmodiumfalciparumdevelopment AT mariusjentzsch metabolicbalancingbymir276shapesthemosquitoreproductivecycleandplasmodiumfalciparumdevelopment AT sylwiakierszniowska metabolicbalancingbymir276shapesthemosquitoreproductivecycleandplasmodiumfalciparumdevelopment AT elenaalevashina metabolicbalancingbymir276shapesthemosquitoreproductivecycleandplasmodiumfalciparumdevelopment |
_version_ |
1718390879923732480 |