Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development

Plasmodium growth is adapted to the reproductive cycle of mosquitoes, but underlying mechanisms are unclear. Here, Lampe et al. show that the blood-meal induced miR-276 balances the termination of the mosquito amino acid catabolism and egg development, providing nutrients for Plasmodium sporozoite d...

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Main Authors:	Lena Lampe, Marius Jentzsch, Sylwia Kierszniowska, Elena A. Levashina
Format:	article
Language:	EN
Published:	Nature Portfolio 2019
Subjects:	Science Q
Online Access:	https://doaj.org/article/23f1a323f4ee4ef29a1a1b5a9d1e81c3
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id	oai:doaj.org-article:23f1a323f4ee4ef29a1a1b5a9d1e81c3
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spelling	oai:doaj.org-article:23f1a323f4ee4ef29a1a1b5a9d1e81c32021-12-02T14:38:44ZMetabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development10.1038/s41467-019-13627-y2041-1723https://doaj.org/article/23f1a323f4ee4ef29a1a1b5a9d1e81c32019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13627-yhttps://doaj.org/toc/2041-1723Plasmodium growth is adapted to the reproductive cycle of mosquitoes, but underlying mechanisms are unclear. Here, Lampe et al. show that the blood-meal induced miR-276 balances the termination of the mosquito amino acid catabolism and egg development, providing nutrients for Plasmodium sporozoite development.Lena LampeMarius JentzschSylwia KierszniowskaElena A. LevashinaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Lena Lampe Marius Jentzsch Sylwia Kierszniowska Elena A. Levashina Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development
description	Plasmodium growth is adapted to the reproductive cycle of mosquitoes, but underlying mechanisms are unclear. Here, Lampe et al. show that the blood-meal induced miR-276 balances the termination of the mosquito amino acid catabolism and egg development, providing nutrients for Plasmodium sporozoite development.
format	article
author	Lena Lampe Marius Jentzsch Sylwia Kierszniowska Elena A. Levashina
author_facet	Lena Lampe Marius Jentzsch Sylwia Kierszniowska Elena A. Levashina
author_sort	Lena Lampe
title	Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development
title_short	Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development
title_full	Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development
title_fullStr	Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development
title_full_unstemmed	Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development
title_sort	metabolic balancing by mir-276 shapes the mosquito reproductive cycle and plasmodium falciparum development
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/23f1a323f4ee4ef29a1a1b5a9d1e81c3
work_keys_str_mv	AT lenalampe metabolicbalancingbymir276shapesthemosquitoreproductivecycleandplasmodiumfalciparumdevelopment AT mariusjentzsch metabolicbalancingbymir276shapesthemosquitoreproductivecycleandplasmodiumfalciparumdevelopment AT sylwiakierszniowska metabolicbalancingbymir276shapesthemosquitoreproductivecycleandplasmodiumfalciparumdevelopment AT elenaalevashina metabolicbalancingbymir276shapesthemosquitoreproductivecycleandplasmodiumfalciparumdevelopment
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Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development

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