Long-term prognosis of vascular access in hemodialysis patients with systemic lupus erythematosus: a retrospective cohort study

Abstract Patients with systemic lupus erythematosus (SLE) have a higher risk of vascular complications. This retrospective cohort study aimed to analyze the differences in the risk of arteriovenous fistula or graft (AVF/AVG) dysfunction in hemodialysis patients with and without SLE from Taiwan’s Nat...

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Autores principales:	Fan-Yu Chen, Chun-Fan Chen, Ann Charis Tan, Chia-Hao Chan, Fu-An Chen, Wen-Sheng Liu, Tz-Heng Chen, Shuo-Ming Ou, Szu-Yuan Li, Ming-Tsun Tsai, Yung-Tai Chen, Chih-Ching Lin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/24016fa801d84ba7822f28dbf1aba9ae
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spelling	oai:doaj.org-article:24016fa801d84ba7822f28dbf1aba9ae2021-12-02T17:40:49ZLong-term prognosis of vascular access in hemodialysis patients with systemic lupus erythematosus: a retrospective cohort study10.1038/s41598-021-92005-52045-2322https://doaj.org/article/24016fa801d84ba7822f28dbf1aba9ae2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-92005-5https://doaj.org/toc/2045-2322Abstract Patients with systemic lupus erythematosus (SLE) have a higher risk of vascular complications. This retrospective cohort study aimed to analyze the differences in the risk of arteriovenous fistula or graft (AVF/AVG) dysfunction in hemodialysis patients with and without SLE from Taiwan’s National Health Insurance Database over a 10-year period. AVF/AVG dysfunction is defined as the occurrence of the first episode of intervention after vascular access creation. A total of 1366 HD patients with SLE had higher incidence rates of AVF/AVG dysfunction than 4098 non-SLE HD patients in the following 4 periods: (1) after 1 year (incidence rates = 15.21% and 13.01%, respectively; subdistribution hazard ratio (SHR) = 1.16; P = 0.007), (2) 1st-to-10th-year period (15.36% and 13.25%; SHR = 1.16; P = 0.007), (3) 5th-to-10th-year period (11.91% and 8.1%; SHR = 1.42; P = 0.003), and (4) overall period (23.53% and 21.66%; SHR = 1.09; P = 0.027). In conclusion, there were significantly higher incidence rates of AVF/AVG dysfunction in SLE patients during the long-term follow-up period. Vascular access function should be monitored regularly by clinical examinations, especially after 1 year and during 5 to 10 years, to improve AVF/AVG patency and dialysis adequacy in SLE patients undergoing maintenance hemodialysis.Fan-Yu ChenChun-Fan ChenAnn Charis TanChia-Hao ChanFu-An ChenWen-Sheng LiuTz-Heng ChenShuo-Ming OuSzu-Yuan LiMing-Tsun TsaiYung-Tai ChenChih-Ching LinNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Fan-Yu Chen Chun-Fan Chen Ann Charis Tan Chia-Hao Chan Fu-An Chen Wen-Sheng Liu Tz-Heng Chen Shuo-Ming Ou Szu-Yuan Li Ming-Tsun Tsai Yung-Tai Chen Chih-Ching Lin Long-term prognosis of vascular access in hemodialysis patients with systemic lupus erythematosus: a retrospective cohort study
description	Abstract Patients with systemic lupus erythematosus (SLE) have a higher risk of vascular complications. This retrospective cohort study aimed to analyze the differences in the risk of arteriovenous fistula or graft (AVF/AVG) dysfunction in hemodialysis patients with and without SLE from Taiwan’s National Health Insurance Database over a 10-year period. AVF/AVG dysfunction is defined as the occurrence of the first episode of intervention after vascular access creation. A total of 1366 HD patients with SLE had higher incidence rates of AVF/AVG dysfunction than 4098 non-SLE HD patients in the following 4 periods: (1) after 1 year (incidence rates = 15.21% and 13.01%, respectively; subdistribution hazard ratio (SHR) = 1.16; P = 0.007), (2) 1st-to-10th-year period (15.36% and 13.25%; SHR = 1.16; P = 0.007), (3) 5th-to-10th-year period (11.91% and 8.1%; SHR = 1.42; P = 0.003), and (4) overall period (23.53% and 21.66%; SHR = 1.09; P = 0.027). In conclusion, there were significantly higher incidence rates of AVF/AVG dysfunction in SLE patients during the long-term follow-up period. Vascular access function should be monitored regularly by clinical examinations, especially after 1 year and during 5 to 10 years, to improve AVF/AVG patency and dialysis adequacy in SLE patients undergoing maintenance hemodialysis.
format	article
author	Fan-Yu Chen Chun-Fan Chen Ann Charis Tan Chia-Hao Chan Fu-An Chen Wen-Sheng Liu Tz-Heng Chen Shuo-Ming Ou Szu-Yuan Li Ming-Tsun Tsai Yung-Tai Chen Chih-Ching Lin
author_facet	Fan-Yu Chen Chun-Fan Chen Ann Charis Tan Chia-Hao Chan Fu-An Chen Wen-Sheng Liu Tz-Heng Chen Shuo-Ming Ou Szu-Yuan Li Ming-Tsun Tsai Yung-Tai Chen Chih-Ching Lin
author_sort	Fan-Yu Chen
title	Long-term prognosis of vascular access in hemodialysis patients with systemic lupus erythematosus: a retrospective cohort study
title_short	Long-term prognosis of vascular access in hemodialysis patients with systemic lupus erythematosus: a retrospective cohort study
title_full	Long-term prognosis of vascular access in hemodialysis patients with systemic lupus erythematosus: a retrospective cohort study
title_fullStr	Long-term prognosis of vascular access in hemodialysis patients with systemic lupus erythematosus: a retrospective cohort study
title_full_unstemmed	Long-term prognosis of vascular access in hemodialysis patients with systemic lupus erythematosus: a retrospective cohort study
title_sort	long-term prognosis of vascular access in hemodialysis patients with systemic lupus erythematosus: a retrospective cohort study
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/24016fa801d84ba7822f28dbf1aba9ae
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Long-term prognosis of vascular access in hemodialysis patients with systemic lupus erythematosus: a retrospective cohort study

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