Endogenous PCSK9 may influence circulating CD45neg/CD34bright and CD45neg/CD34bright/CD146neg cells in patients with type 2 diabetes mellitus

Endogenous PCSK9 may influence circulating CD45neg/CD34bright and CD45neg/CD34bright/CD146neg cells in patients with type 2 diabetes mellitus

Abstract Protease proprotein convertase subtilisin/kexin type 9 (PCSK9) is a regulator of LDL cholesterol clearance and has been associated with cardiovascular risk. PCSK9 inhibitors increase in vivo circulating endothelial progenitor cells (EPCs), a subtype of immature cells involved in ongoing end...

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Main Authors: Romina Tripaldi, Paola Lanuti, Paola Giustina Simeone, Rossella Liani, Giuseppina Bologna, Sonia Ciotti, Pasquale Simeone, Augusto Di Castelnuovo, Marco Marchisio, Francesco Cipollone, Francesca Santilli
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/240420d0916c4f7da323f4207dc7fb87
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https://doaj.org/article/240420d0916c4f7da323f4207dc7fb87

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