Learning mutational signatures and their multidimensional genomic properties with TensorSignatures
Currently available tools for the analysis of mutational signatures do not make use of all possible genomic properties aside from mutation patterns. Here the authors present TensorSignatures, an efficient framework that jointly infers mutational signatures and their genomic determinants.
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Main Authors: | , , , |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Subjects: | |
Online Access: | https://doaj.org/article/2405297639f64e50aa0d98e47f6b0bb5 |
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Summary: | Currently available tools for the analysis of mutational signatures do not make use of all possible genomic properties aside from mutation patterns. Here the authors present TensorSignatures, an efficient framework that jointly infers mutational signatures and their genomic determinants. |
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