Conditional and interaction gene-set analysis reveals novel functional pathways for blood pressure

Gene-set analysis (GSA) is widely used to infer functional and biological properties of a gene set. Here, the authors develop a conditional and interaction gene-set analysis approach that can considerably refine results from traditional GSA.

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Detalles Bibliográficos
Autores principales: Christiaan A. de Leeuw, Sven Stringer, Ilona A. Dekkers, Tom Heskes, Danielle Posthuma
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/241c1127ce014dceaa058d324b4c6adf
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Descripción
Sumario:Gene-set analysis (GSA) is widely used to infer functional and biological properties of a gene set. Here, the authors develop a conditional and interaction gene-set analysis approach that can considerably refine results from traditional GSA.