STAT3 governs the HIF-1α response in IL-15 primed human NK cells
Abstract Natural killer (NK) cells mediate innate host defense against microbial infection and cancer. Hypoxia and low glucose are characteristic for these tissue lesions but do not affect early interferon (IFN) γ and CC chemokine release by interleukin 15 (IL-15) primed human NK cells in vitro. Hyp...
Guardado en:
Autores principales: | Anna Coulibaly, Sonia Y. Velásquez, Nina Kassner, Jutta Schulte, Maria Vittoria Barbarossa, Holger A. Lindner |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/241d538460a74c8eb2e876ba1dfab688 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
HIF1α is required for NK cell metabolic adaptation during virus infection
por: Francisco Victorino, et al.
Publicado: (2021) -
The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling
por: Eui Jung Moon, et al.
Publicado: (2021) -
Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells
por: Charlène Niogret, et al.
Publicado: (2019) -
HIF1α and HIF2α exert distinct nutrient preferences in renal cells.
por: Alexandra Arreola, et al.
Publicado: (2014) -
IL-10 suppression of NK/DC crosstalk leads to poor priming of MCMV-specific CD4 T cells and prolonged MCMV persistence.
por: Sanja Mandaric, et al.
Publicado: (2012)