Structural mechanism for gating of a eukaryotic mechanosensitive channel of small conductance
Mechanosensitive channels transduce physical force into electrochemical signaling in processes such as hearing, touch, proprioception, osmoregulation, and morphogenesis. Here, authors use cryo-electron microscopy to provide structural insights into the mechanical gating mechanism.
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Nature Portfolio
2020
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oai:doaj.org-article:24278fd6df614c24883c81fc709a65802021-12-02T16:17:53ZStructural mechanism for gating of a eukaryotic mechanosensitive channel of small conductance10.1038/s41467-020-17538-12041-1723https://doaj.org/article/24278fd6df614c24883c81fc709a65802020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17538-1https://doaj.org/toc/2041-1723Mechanosensitive channels transduce physical force into electrochemical signaling in processes such as hearing, touch, proprioception, osmoregulation, and morphogenesis. Here, authors use cryo-electron microscopy to provide structural insights into the mechanical gating mechanism.Zengqin DengGrigory MaksaevAngela M. SchlegelJingying ZhangMichael RauJames A. J. FitzpatrickElizabeth S. HaswellPeng YuanNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020) |
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Science Q Zengqin Deng Grigory Maksaev Angela M. Schlegel Jingying Zhang Michael Rau James A. J. Fitzpatrick Elizabeth S. Haswell Peng Yuan Structural mechanism for gating of a eukaryotic mechanosensitive channel of small conductance |
description |
Mechanosensitive channels transduce physical force into electrochemical signaling in processes such as hearing, touch, proprioception, osmoregulation, and morphogenesis. Here, authors use cryo-electron microscopy to provide structural insights into the mechanical gating mechanism. |
format |
article |
author |
Zengqin Deng Grigory Maksaev Angela M. Schlegel Jingying Zhang Michael Rau James A. J. Fitzpatrick Elizabeth S. Haswell Peng Yuan |
author_facet |
Zengqin Deng Grigory Maksaev Angela M. Schlegel Jingying Zhang Michael Rau James A. J. Fitzpatrick Elizabeth S. Haswell Peng Yuan |
author_sort |
Zengqin Deng |
title |
Structural mechanism for gating of a eukaryotic mechanosensitive channel of small conductance |
title_short |
Structural mechanism for gating of a eukaryotic mechanosensitive channel of small conductance |
title_full |
Structural mechanism for gating of a eukaryotic mechanosensitive channel of small conductance |
title_fullStr |
Structural mechanism for gating of a eukaryotic mechanosensitive channel of small conductance |
title_full_unstemmed |
Structural mechanism for gating of a eukaryotic mechanosensitive channel of small conductance |
title_sort |
structural mechanism for gating of a eukaryotic mechanosensitive channel of small conductance |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/24278fd6df614c24883c81fc709a6580 |
work_keys_str_mv |
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1718384219052310528 |