Structural mechanism for gating of a eukaryotic mechanosensitive channel of small conductance

Mechanosensitive channels transduce physical force into electrochemical signaling in processes such as hearing, touch, proprioception, osmoregulation, and morphogenesis. Here, authors use cryo-electron microscopy to provide structural insights into the mechanical gating mechanism.

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Autores principales:	Zengqin Deng, Grigory Maksaev, Angela M. Schlegel, Jingying Zhang, Michael Rau, James A. J. Fitzpatrick, Elizabeth S. Haswell, Peng Yuan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/24278fd6df614c24883c81fc709a6580
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spelling	oai:doaj.org-article:24278fd6df614c24883c81fc709a65802021-12-02T16:17:53ZStructural mechanism for gating of a eukaryotic mechanosensitive channel of small conductance10.1038/s41467-020-17538-12041-1723https://doaj.org/article/24278fd6df614c24883c81fc709a65802020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17538-1https://doaj.org/toc/2041-1723Mechanosensitive channels transduce physical force into electrochemical signaling in processes such as hearing, touch, proprioception, osmoregulation, and morphogenesis. Here, authors use cryo-electron microscopy to provide structural insights into the mechanical gating mechanism.Zengqin DengGrigory MaksaevAngela M. SchlegelJingying ZhangMichael RauJames A. J. FitzpatrickElizabeth S. HaswellPeng YuanNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Zengqin Deng Grigory Maksaev Angela M. Schlegel Jingying Zhang Michael Rau James A. J. Fitzpatrick Elizabeth S. Haswell Peng Yuan Structural mechanism for gating of a eukaryotic mechanosensitive channel of small conductance
description	Mechanosensitive channels transduce physical force into electrochemical signaling in processes such as hearing, touch, proprioception, osmoregulation, and morphogenesis. Here, authors use cryo-electron microscopy to provide structural insights into the mechanical gating mechanism.
format	article
author	Zengqin Deng Grigory Maksaev Angela M. Schlegel Jingying Zhang Michael Rau James A. J. Fitzpatrick Elizabeth S. Haswell Peng Yuan
author_facet	Zengqin Deng Grigory Maksaev Angela M. Schlegel Jingying Zhang Michael Rau James A. J. Fitzpatrick Elizabeth S. Haswell Peng Yuan
author_sort	Zengqin Deng
title	Structural mechanism for gating of a eukaryotic mechanosensitive channel of small conductance
title_short	Structural mechanism for gating of a eukaryotic mechanosensitive channel of small conductance
title_full	Structural mechanism for gating of a eukaryotic mechanosensitive channel of small conductance
title_fullStr	Structural mechanism for gating of a eukaryotic mechanosensitive channel of small conductance
title_full_unstemmed	Structural mechanism for gating of a eukaryotic mechanosensitive channel of small conductance
title_sort	structural mechanism for gating of a eukaryotic mechanosensitive channel of small conductance
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/24278fd6df614c24883c81fc709a6580
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_version_	1718384219052310528

Structural mechanism for gating of a eukaryotic mechanosensitive channel of small conductance

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