Prescribing frequency and adherence to statins in outpatients with type 2 diabetes mellitus and comorbid cardiovascular diseases

BACKGROUND: Due to the high rate of growth in the incidence and burden of cardiovascular complications, type 2 diabetes mellitus (T2DM) is a significant medical problem in the world. Even in the absence of cardiovascular disease (CVD), patients with T2DM are classified as high and very high risk. In...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Victoriya N. Serebryakova, Elena A. Golovina, Artem V. Kaveshnikov, Vladimir S. Kaveshnikov
Formato:	article
Lenguaje:	EN RU
Publicado:	Endocrinology Research Centre 2021
Materias:	diabetes mellitus cardiovascular disease statins prescription frequency adherence to treatment comorbidity Nutritional diseases. Deficiency diseases RC620-627
Acceso en línea:	https://doaj.org/article/2428d33350874b619963e3ac1117b050
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:2428d33350874b619963e3ac1117b050
record_format	dspace
spelling	oai:doaj.org-article:2428d33350874b619963e3ac1117b0502021-11-14T09:00:23ZPrescribing frequency and adherence to statins in outpatients with type 2 diabetes mellitus and comorbid cardiovascular diseases2072-03512072-037810.14341/DM12563https://doaj.org/article/2428d33350874b619963e3ac1117b0502021-01-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/12563https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378BACKGROUND: Due to the high rate of growth in the incidence and burden of cardiovascular complications, type 2 diabetes mellitus (T2DM) is a significant medical problem in the world. Even in the absence of cardiovascular disease (CVD), patients with T2DM are classified as high and very high risk. In addition to glycemic control, an extremely important aspect of managing this group of patients is prevention of cardiovascular complications. T2DM and hyperlipidemia determines the target group for statins. At the same time, little is known about the frequency of administration of this class of drugs among people with T2DM.AIM: To study prescribing frequency and adherence to statins in outpatients with T2DM and comorbid cardiovascular diseases.METHODS: 156 patients with type 2 diabetes (87.2% — women, average age — 65.2 years) were examined as part of an outpatient appointment with an endocrinologist at the city polyclinic ofTomsk. We used a standard questionnaire compiled on the basis of adapted international methods, including information on cardiac pathology, medications, income level, and Morisky-Green test. Anthropometric parameters, fasting plasma glucose, glycated hemoglobin, lipid spectrum parameters were measured. Methods of parametric and nonparametric statistics were used for comparisons.RESULTS: Statins were prescribed to 45.0% of the surveyed, and 47.0% of them were constantly taking statins. In 41 and 39% of cases, statins were prescribed by an endocrinologist and a cardiologist, respectively. Those taking statins were characterized by a more severe functional class of angina pectoris (p=0.03), a higher prior myocardial infarction rate (p=0.01). For other concomitant diseases, and also indicators of carbohydrate metabolism, differences between the groups were not revealed. One third of patients were adherent (3–4 points), 2/3 were not adherent to treatment (0–2 points), respectively. Patients with incomes between 1 and 2 cost of living took statins more often than the rest (p=0.021).CONCLUSION: An insufficient frequency of prescription and adherence to statin therapy in patients with T2DM was revealed. In most cases, statins were prescribed by an endocrinologist or cardiologist. Functional class of angina pectoris, prior myocardial infarction and moderate income were associated with more frequent use of statins. To increase the coverage of patients with T2DM with statin treatment, more attention needs to be paid to the issues of CVD prevention from both medical professionals and patients.Victoriya N. SerebryakovaElena A. GolovinaArtem V. KaveshnikovVladimir S. KaveshnikovEndocrinology Research Centrearticlediabetes mellituscardiovascular diseasestatinsprescription frequencyadherence to treatmentcomorbidityNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 23, Iss 5, Pp 434-441 (2021)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	diabetes mellitus cardiovascular disease statins prescription frequency adherence to treatment comorbidity Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	diabetes mellitus cardiovascular disease statins prescription frequency adherence to treatment comorbidity Nutritional diseases. Deficiency diseases RC620-627 Victoriya N. Serebryakova Elena A. Golovina Artem V. Kaveshnikov Vladimir S. Kaveshnikov Prescribing frequency and adherence to statins in outpatients with type 2 diabetes mellitus and comorbid cardiovascular diseases
description	BACKGROUND: Due to the high rate of growth in the incidence and burden of cardiovascular complications, type 2 diabetes mellitus (T2DM) is a significant medical problem in the world. Even in the absence of cardiovascular disease (CVD), patients with T2DM are classified as high and very high risk. In addition to glycemic control, an extremely important aspect of managing this group of patients is prevention of cardiovascular complications. T2DM and hyperlipidemia determines the target group for statins. At the same time, little is known about the frequency of administration of this class of drugs among people with T2DM.AIM: To study prescribing frequency and adherence to statins in outpatients with T2DM and comorbid cardiovascular diseases.METHODS: 156 patients with type 2 diabetes (87.2% — women, average age — 65.2 years) were examined as part of an outpatient appointment with an endocrinologist at the city polyclinic ofTomsk. We used a standard questionnaire compiled on the basis of adapted international methods, including information on cardiac pathology, medications, income level, and Morisky-Green test. Anthropometric parameters, fasting plasma glucose, glycated hemoglobin, lipid spectrum parameters were measured. Methods of parametric and nonparametric statistics were used for comparisons.RESULTS: Statins were prescribed to 45.0% of the surveyed, and 47.0% of them were constantly taking statins. In 41 and 39% of cases, statins were prescribed by an endocrinologist and a cardiologist, respectively. Those taking statins were characterized by a more severe functional class of angina pectoris (p=0.03), a higher prior myocardial infarction rate (p=0.01). For other concomitant diseases, and also indicators of carbohydrate metabolism, differences between the groups were not revealed. One third of patients were adherent (3–4 points), 2/3 were not adherent to treatment (0–2 points), respectively. Patients with incomes between 1 and 2 cost of living took statins more often than the rest (p=0.021).CONCLUSION: An insufficient frequency of prescription and adherence to statin therapy in patients with T2DM was revealed. In most cases, statins were prescribed by an endocrinologist or cardiologist. Functional class of angina pectoris, prior myocardial infarction and moderate income were associated with more frequent use of statins. To increase the coverage of patients with T2DM with statin treatment, more attention needs to be paid to the issues of CVD prevention from both medical professionals and patients.
format	article
author	Victoriya N. Serebryakova Elena A. Golovina Artem V. Kaveshnikov Vladimir S. Kaveshnikov
author_facet	Victoriya N. Serebryakova Elena A. Golovina Artem V. Kaveshnikov Vladimir S. Kaveshnikov
author_sort	Victoriya N. Serebryakova
title	Prescribing frequency and adherence to statins in outpatients with type 2 diabetes mellitus and comorbid cardiovascular diseases
title_short	Prescribing frequency and adherence to statins in outpatients with type 2 diabetes mellitus and comorbid cardiovascular diseases
title_full	Prescribing frequency and adherence to statins in outpatients with type 2 diabetes mellitus and comorbid cardiovascular diseases
title_fullStr	Prescribing frequency and adherence to statins in outpatients with type 2 diabetes mellitus and comorbid cardiovascular diseases
title_full_unstemmed	Prescribing frequency and adherence to statins in outpatients with type 2 diabetes mellitus and comorbid cardiovascular diseases
title_sort	prescribing frequency and adherence to statins in outpatients with type 2 diabetes mellitus and comorbid cardiovascular diseases
publisher	Endocrinology Research Centre
publishDate	2021
url	https://doaj.org/article/2428d33350874b619963e3ac1117b050
work_keys_str_mv	AT victoriyanserebryakova prescribingfrequencyandadherencetostatinsinoutpatientswithtype2diabetesmellitusandcomorbidcardiovasculardiseases AT elenaagolovina prescribingfrequencyandadherencetostatinsinoutpatientswithtype2diabetesmellitusandcomorbidcardiovasculardiseases AT artemvkaveshnikov prescribingfrequencyandadherencetostatinsinoutpatientswithtype2diabetesmellitusandcomorbidcardiovasculardiseases AT vladimirskaveshnikov prescribingfrequencyandadherencetostatinsinoutpatientswithtype2diabetesmellitusandcomorbidcardiovasculardiseases
_version_	1718429454285406208

Prescribing frequency and adherence to statins in outpatients with type 2 diabetes mellitus and comorbid cardiovascular diseases

Ejemplares similares