Neuroplastin deletion in glutamatergic neurons impairs selective brain functions and calcium regulation: implication for cognitive deterioration

Neuroplastin deletion in glutamatergic neurons impairs selective brain functions and calcium regulation: implication for cognitive deterioration

Abstract The cell adhesion molecule neuroplastin (Np) is a novel candidate to influence human intelligence. Np-deficient mice display complex cognitive deficits and reduced levels of Plasma Membrane Ca2+ ATPases (PMCAs), an essential regulator of the intracellular Ca2+ concentration ([iCa2+]) and ne...

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Autores principales: Rodrigo Herrera-Molina, Kristina Mlinac-Jerkovic, Katarina Ilic, Franziska Stöber, Sampath Kumar Vemula, Mauricio Sandoval, Natasa Jovanov Milosevic, Goran Simic, Karl-Heinz Smalla, Jürgen Goldschmidt, Svjetlana Kalanj Bognar, Dirk Montag
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/242c8b715c3a4890a78cba8ca5160c63
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