Mps1 kinase-dependent Sgo2 centromere localisation mediates cohesin protection in mouse oocyte meiosis I

In meiosis I centromeric cohesin is protected by Sgo2 from Separase-mediated cleavage ensuring that sister chromatids are kept together until their separation in meiosis II. Here the authors demonstrate that Bub1 and Mps1 kinase activities are required for Sgo2 localisation to the centromere region.

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Autores principales:	Warif El Yakoubi, Eulalie Buffin, Damien Cladière, Yulia Gryaznova, Inés Berenguer, Sandra A. Touati, Rocío Gómez, José A. Suja, Jan M. van Deursen, Katja Wassmann
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/246315e51c7f4b9ea41e856a14b0f70e
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spelling	oai:doaj.org-article:246315e51c7f4b9ea41e856a14b0f70e2021-12-02T15:39:06ZMps1 kinase-dependent Sgo2 centromere localisation mediates cohesin protection in mouse oocyte meiosis I10.1038/s41467-017-00774-32041-1723https://doaj.org/article/246315e51c7f4b9ea41e856a14b0f70e2017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00774-3https://doaj.org/toc/2041-1723In meiosis I centromeric cohesin is protected by Sgo2 from Separase-mediated cleavage ensuring that sister chromatids are kept together until their separation in meiosis II. Here the authors demonstrate that Bub1 and Mps1 kinase activities are required for Sgo2 localisation to the centromere region.Warif El YakoubiEulalie BuffinDamien CladièreYulia GryaznovaInés BerenguerSandra A. TouatiRocío GómezJosé A. SujaJan M. van DeursenKatja WassmannNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Warif El Yakoubi Eulalie Buffin Damien Cladière Yulia Gryaznova Inés Berenguer Sandra A. Touati Rocío Gómez José A. Suja Jan M. van Deursen Katja Wassmann Mps1 kinase-dependent Sgo2 centromere localisation mediates cohesin protection in mouse oocyte meiosis I
description	In meiosis I centromeric cohesin is protected by Sgo2 from Separase-mediated cleavage ensuring that sister chromatids are kept together until their separation in meiosis II. Here the authors demonstrate that Bub1 and Mps1 kinase activities are required for Sgo2 localisation to the centromere region.
format	article
author	Warif El Yakoubi Eulalie Buffin Damien Cladière Yulia Gryaznova Inés Berenguer Sandra A. Touati Rocío Gómez José A. Suja Jan M. van Deursen Katja Wassmann
author_facet	Warif El Yakoubi Eulalie Buffin Damien Cladière Yulia Gryaznova Inés Berenguer Sandra A. Touati Rocío Gómez José A. Suja Jan M. van Deursen Katja Wassmann
author_sort	Warif El Yakoubi
title	Mps1 kinase-dependent Sgo2 centromere localisation mediates cohesin protection in mouse oocyte meiosis I
title_short	Mps1 kinase-dependent Sgo2 centromere localisation mediates cohesin protection in mouse oocyte meiosis I
title_full	Mps1 kinase-dependent Sgo2 centromere localisation mediates cohesin protection in mouse oocyte meiosis I
title_fullStr	Mps1 kinase-dependent Sgo2 centromere localisation mediates cohesin protection in mouse oocyte meiosis I
title_full_unstemmed	Mps1 kinase-dependent Sgo2 centromere localisation mediates cohesin protection in mouse oocyte meiosis I
title_sort	mps1 kinase-dependent sgo2 centromere localisation mediates cohesin protection in mouse oocyte meiosis i
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/246315e51c7f4b9ea41e856a14b0f70e
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Mps1 kinase-dependent Sgo2 centromere localisation mediates cohesin protection in mouse oocyte meiosis I

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