ER/K linked GPCR-G protein fusions systematically modulate second messenger response in cells

ER/K linked GPCR-G protein fusions systematically modulate second messenger response in cells

Abstract FRET and BRET approaches are well established for detecting ligand induced GPCR-G protein interactions in cells. Currently, FRET/BRET assays rely on co-expression of GPCR and G protein, and hence depend on the stoichiometry and expression levels of the donor and acceptor probes. On the othe...

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Autores principales: Rabia U. Malik, Matthew Dysthe, Michael Ritt, Roger K. Sunahara, Sivaraj Sivaramakrishnan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/246552c8efa54c19bc36a88af7a47811
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