CRISPR-Cas Systems for Detection of Nucleic Acids: PCR Empire now has a Vigorous Rival!

Rapid and accurate detection of nucleic acids is essential in many fields of modern biology and medical diagnosis of pathogens. PCR has some disadvantages for performing this task, and therefore demand for an alternative is highly appreciated. Recently, CRISPR-Cas systems have been introduced as a r...

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Autor principal: Roham Deyhimfar
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Publicado: Urology Research Center 2021
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Acceso en línea:https://doaj.org/article/246fe07be27b4dd0912b0e2390894b42
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spelling oai:doaj.org-article:246fe07be27b4dd0912b0e2390894b422021-11-30T08:47:21ZCRISPR-Cas Systems for Detection of Nucleic Acids: PCR Empire now has a Vigorous Rival!10.22034/TRU.2021.310841.10852717-042Xhttps://doaj.org/article/246fe07be27b4dd0912b0e2390894b422021-11-01T00:00:00Zhttps://www.transresurology.com/article_139590.htmlhttps://doaj.org/toc/2717-042XRapid and accurate detection of nucleic acids is essential in many fields of modern biology and medical diagnosis of pathogens. PCR has some disadvantages for performing this task, and therefore demand for an alternative is highly appreciated. Recently, CRISPR-Cas systems have been introduced as a rapid, sensitive, and efficient method for nucleic acid detection. This editorial article reviews mechanisms of action and preclinical results of SHERLOCK and DETECTR as two significant forms of CRISPR-Cas systems for nucleic acid detection.Roham DeyhimfarUrology Research CenterarticlecrisprsherlockdetectrDiseases of the genitourinary system. UrologyRC870-923ENTranslational Research in Urology, Vol 3, Iss 4, Pp 143-145 (2021)
institution DOAJ
collection DOAJ
language EN
topic crispr
sherlock
detectr
Diseases of the genitourinary system. Urology
RC870-923
spellingShingle crispr
sherlock
detectr
Diseases of the genitourinary system. Urology
RC870-923
Roham Deyhimfar
CRISPR-Cas Systems for Detection of Nucleic Acids: PCR Empire now has a Vigorous Rival!
description Rapid and accurate detection of nucleic acids is essential in many fields of modern biology and medical diagnosis of pathogens. PCR has some disadvantages for performing this task, and therefore demand for an alternative is highly appreciated. Recently, CRISPR-Cas systems have been introduced as a rapid, sensitive, and efficient method for nucleic acid detection. This editorial article reviews mechanisms of action and preclinical results of SHERLOCK and DETECTR as two significant forms of CRISPR-Cas systems for nucleic acid detection.
format article
author Roham Deyhimfar
author_facet Roham Deyhimfar
author_sort Roham Deyhimfar
title CRISPR-Cas Systems for Detection of Nucleic Acids: PCR Empire now has a Vigorous Rival!
title_short CRISPR-Cas Systems for Detection of Nucleic Acids: PCR Empire now has a Vigorous Rival!
title_full CRISPR-Cas Systems for Detection of Nucleic Acids: PCR Empire now has a Vigorous Rival!
title_fullStr CRISPR-Cas Systems for Detection of Nucleic Acids: PCR Empire now has a Vigorous Rival!
title_full_unstemmed CRISPR-Cas Systems for Detection of Nucleic Acids: PCR Empire now has a Vigorous Rival!
title_sort crispr-cas systems for detection of nucleic acids: pcr empire now has a vigorous rival!
publisher Urology Research Center
publishDate 2021
url https://doaj.org/article/246fe07be27b4dd0912b0e2390894b42
work_keys_str_mv AT rohamdeyhimfar crisprcassystemsfordetectionofnucleicacidspcrempirenowhasavigorousrival
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