CRISPR-Cas Systems for Detection of Nucleic Acids: PCR Empire now has a Vigorous Rival!
Rapid and accurate detection of nucleic acids is essential in many fields of modern biology and medical diagnosis of pathogens. PCR has some disadvantages for performing this task, and therefore demand for an alternative is highly appreciated. Recently, CRISPR-Cas systems have been introduced as a r...
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Urology Research Center
2021
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oai:doaj.org-article:246fe07be27b4dd0912b0e2390894b422021-11-30T08:47:21ZCRISPR-Cas Systems for Detection of Nucleic Acids: PCR Empire now has a Vigorous Rival!10.22034/TRU.2021.310841.10852717-042Xhttps://doaj.org/article/246fe07be27b4dd0912b0e2390894b422021-11-01T00:00:00Zhttps://www.transresurology.com/article_139590.htmlhttps://doaj.org/toc/2717-042XRapid and accurate detection of nucleic acids is essential in many fields of modern biology and medical diagnosis of pathogens. PCR has some disadvantages for performing this task, and therefore demand for an alternative is highly appreciated. Recently, CRISPR-Cas systems have been introduced as a rapid, sensitive, and efficient method for nucleic acid detection. This editorial article reviews mechanisms of action and preclinical results of SHERLOCK and DETECTR as two significant forms of CRISPR-Cas systems for nucleic acid detection.Roham DeyhimfarUrology Research CenterarticlecrisprsherlockdetectrDiseases of the genitourinary system. UrologyRC870-923ENTranslational Research in Urology, Vol 3, Iss 4, Pp 143-145 (2021) |
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crispr sherlock detectr Diseases of the genitourinary system. Urology RC870-923 |
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crispr sherlock detectr Diseases of the genitourinary system. Urology RC870-923 Roham Deyhimfar CRISPR-Cas Systems for Detection of Nucleic Acids: PCR Empire now has a Vigorous Rival! |
description |
Rapid and accurate detection of nucleic acids is essential in many fields of modern biology and medical diagnosis of pathogens. PCR has some disadvantages for performing this task, and therefore demand for an alternative is highly appreciated. Recently, CRISPR-Cas systems have been introduced as a rapid, sensitive, and efficient method for nucleic acid detection. This editorial article reviews mechanisms of action and preclinical results of SHERLOCK and DETECTR as two significant forms of CRISPR-Cas systems for nucleic acid detection. |
format |
article |
author |
Roham Deyhimfar |
author_facet |
Roham Deyhimfar |
author_sort |
Roham Deyhimfar |
title |
CRISPR-Cas Systems for Detection of Nucleic Acids: PCR Empire now has a Vigorous Rival! |
title_short |
CRISPR-Cas Systems for Detection of Nucleic Acids: PCR Empire now has a Vigorous Rival! |
title_full |
CRISPR-Cas Systems for Detection of Nucleic Acids: PCR Empire now has a Vigorous Rival! |
title_fullStr |
CRISPR-Cas Systems for Detection of Nucleic Acids: PCR Empire now has a Vigorous Rival! |
title_full_unstemmed |
CRISPR-Cas Systems for Detection of Nucleic Acids: PCR Empire now has a Vigorous Rival! |
title_sort |
crispr-cas systems for detection of nucleic acids: pcr empire now has a vigorous rival! |
publisher |
Urology Research Center |
publishDate |
2021 |
url |
https://doaj.org/article/246fe07be27b4dd0912b0e2390894b42 |
work_keys_str_mv |
AT rohamdeyhimfar crisprcassystemsfordetectionofnucleicacidspcrempirenowhasavigorousrival |
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1718406671886188544 |