The Correlation Between Single Nucleotide Polymorphism Patterns and Colorectal Cancer in the Iranian Population

Context: The incidence of colorectal cancer has significantly increased in Iran during the last decade. Accumulating evidence suggeststhat there is a significant correlation between genetic variations such as polymorphisms and colorectal cancer. Therefore,identification of critical polymorphisms rel...

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Autores principales: Mozhdeh Zamani, Seyed Vahid Hosseini, Pooneh Mokarram
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Lenguaje:EN
Publicado: Shiraz University of Medical Sciences 2016
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Acceso en línea:https://doaj.org/article/2470ca539b6c483eafe90bf4acfe6d5c
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spelling oai:doaj.org-article:2470ca539b6c483eafe90bf4acfe6d5c2021-11-15T09:43:59ZThe Correlation Between Single Nucleotide Polymorphism Patterns and Colorectal Cancer in the Iranian Population2783-2430https://doaj.org/article/2470ca539b6c483eafe90bf4acfe6d5c2016-09-01T00:00:00Zhttps://colorectalresearch.sums.ac.ir/article_47146_4c80607f9022203f7df3ea2a58400e1c.pdfhttps://doaj.org/toc/2783-2430Context: The incidence of colorectal cancer has significantly increased in Iran during the last decade. Accumulating evidence suggeststhat there is a significant correlation between genetic variations such as polymorphisms and colorectal cancer. Therefore,identification of critical polymorphisms related to colorectal cancer can contribute to find individuals at high risk of CRC.Evidence Acquisition: The focus of this review was on published articles in English about the association between different singlenucleotide polymorphisms and colorectal cancer in the Iranian population. Evidences were gathered by searching online medicaldatabases including Google scholar, Pubmed, Scopus and Science Direct.Conclusions: Various single nucleotide polymorphisms of critical genes indicated significant association with colorectal cancer inthe Iranian population. New polymorphism markers for high risk individuals have been recognized through further investigationsto reduce the incidence and mortality of colorectal cancer.Mozhdeh ZamaniSeyed Vahid HosseiniPooneh MokarramShiraz University of Medical Sciencesarticlesingle nucleotide polymorphismcolorectal canceriranian populationMedicineRENIranian Journal of Colorectal Research, Vol 4, Iss 3 (2016)
institution DOAJ
collection DOAJ
language EN
topic single nucleotide polymorphism
colorectal cancer
iranian population
Medicine
R
spellingShingle single nucleotide polymorphism
colorectal cancer
iranian population
Medicine
R
Mozhdeh Zamani
Seyed Vahid Hosseini
Pooneh Mokarram
The Correlation Between Single Nucleotide Polymorphism Patterns and Colorectal Cancer in the Iranian Population
description Context: The incidence of colorectal cancer has significantly increased in Iran during the last decade. Accumulating evidence suggeststhat there is a significant correlation between genetic variations such as polymorphisms and colorectal cancer. Therefore,identification of critical polymorphisms related to colorectal cancer can contribute to find individuals at high risk of CRC.Evidence Acquisition: The focus of this review was on published articles in English about the association between different singlenucleotide polymorphisms and colorectal cancer in the Iranian population. Evidences were gathered by searching online medicaldatabases including Google scholar, Pubmed, Scopus and Science Direct.Conclusions: Various single nucleotide polymorphisms of critical genes indicated significant association with colorectal cancer inthe Iranian population. New polymorphism markers for high risk individuals have been recognized through further investigationsto reduce the incidence and mortality of colorectal cancer.
format article
author Mozhdeh Zamani
Seyed Vahid Hosseini
Pooneh Mokarram
author_facet Mozhdeh Zamani
Seyed Vahid Hosseini
Pooneh Mokarram
author_sort Mozhdeh Zamani
title The Correlation Between Single Nucleotide Polymorphism Patterns and Colorectal Cancer in the Iranian Population
title_short The Correlation Between Single Nucleotide Polymorphism Patterns and Colorectal Cancer in the Iranian Population
title_full The Correlation Between Single Nucleotide Polymorphism Patterns and Colorectal Cancer in the Iranian Population
title_fullStr The Correlation Between Single Nucleotide Polymorphism Patterns and Colorectal Cancer in the Iranian Population
title_full_unstemmed The Correlation Between Single Nucleotide Polymorphism Patterns and Colorectal Cancer in the Iranian Population
title_sort correlation between single nucleotide polymorphism patterns and colorectal cancer in the iranian population
publisher Shiraz University of Medical Sciences
publishDate 2016
url https://doaj.org/article/2470ca539b6c483eafe90bf4acfe6d5c
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