Cerebrospinal fluid biomarker and brain biopsy findings in idiopathic normal pressure hydrocephalus.

Cerebrospinal fluid biomarker and brain biopsy findings in idiopathic normal pressure hydrocephalus.

<h4>Background</h4>The significance of amyloid precursor protein (APP) and neuroinflammation in idiopathic normal pressure hydrocephalus (iNPH) and Alzheimer's disease (AD) is unknown.<h4>Objective</h4>To investigate the role of soluble APP (sAPP) and amyloid beta (Aβ) i...

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Autores principales: Okko T Pyykkö, Miikka Lumela, Jaana Rummukainen, Ossi Nerg, Toni T Seppälä, Sanna-Kaisa Herukka, Anne M Koivisto, Irina Alafuzoff, Lakshman Puli, Sakari Savolainen, Hilkka Soininen, Juha E Jääskeläinen, Mikko Hiltunen, Henrik Zetterberg, Ville Leinonen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/2474efa1786747989d060d4f63d44cbd
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