Alarm Clock-Based Reminder for Improving Low Adherence on Option B Plus Antiretroviral Therapy Among HIV Positive Pregnant and Lactating Mothers in Northern Ethiopia

Gebremedhin Gebreegziabher Gebretsadik,1 Hailay Gebretnsae,2 Mulu Ftwi,1 Afewerki Tesfahunegn3 1Department of Midwifery, College of Health Science, Adigrat University, Adigrat, Tigray, Ethiopia; 2Tigray Health Research Institute, Mekelle, Tigray, Ethiopia; 3Department of Epidemiology, College of Hea...

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Autores principales:	Gebretsadik GG, Gebretnsae H, Ftwi M, Tesfahunegn A
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	adherence option b plus art pmtct program ethiopia. Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/247ebf4d2a9b4606b4fbbead1b624224
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spelling	oai:doaj.org-article:247ebf4d2a9b4606b4fbbead1b6242242021-12-02T12:09:07ZAlarm Clock-Based Reminder for Improving Low Adherence on Option B Plus Antiretroviral Therapy Among HIV Positive Pregnant and Lactating Mothers in Northern Ethiopia1179-1373https://doaj.org/article/247ebf4d2a9b4606b4fbbead1b6242242020-11-01T00:00:00Zhttps://www.dovepress.com/alarm-clock-based-reminder-for-improving-low-adherence-on-option-b-plu-peer-reviewed-article-HIVhttps://doaj.org/toc/1179-1373Gebremedhin Gebreegziabher Gebretsadik,1 Hailay Gebretnsae,2 Mulu Ftwi,1 Afewerki Tesfahunegn3 1Department of Midwifery, College of Health Science, Adigrat University, Adigrat, Tigray, Ethiopia; 2Tigray Health Research Institute, Mekelle, Tigray, Ethiopia; 3Department of Epidemiology, College of Health Science, Mekelle University, Mekelle, Tigray, EthiopiaCorrespondence: Gebremedhin Gebreegziabher Gebretsadik Email gebremedhingebretsad@gmail.comBackground: Option B plus antiretroviral therapy (ART) is an approach used to eliminate new Human Immune Deficiency Virus (HIV) infections among infants. Considering the high adherence on Option B plus ART in HIV positive mothers is a crucial part in preventing mother-to-child transmission HIV. Therefore, this study was performed to assess the status of adherence and factors related to Option B plus ART.Methods: A cross-sectional study design was conducted in Eastern zone of Tigrai Region from January to February 2017. Data were collected by using pre-tested structured interviewer-administered questionnaire from 350 participants selected using simple random sampling. Descriptive and binary logistic regression was done during analysis.Results: The overall good adherence status of Option B plus ART among pregnant and lactating mothers was  67.3% [62.3– 72.3%]. Attending formal education (AOR=2.78, 95% CI 1.52– 5.07), traveling for < 1 hour to reach health facility (AOR=2.03, 95% CI 1.19– 3.44), (CD4) count < 350 cells/mm3 (AOR=2.3, 95% CI 1.33– 3.95), starting their Option B plus during pregnancy (AOR= 2.08, 95% CI 1.08– 3.97), taking one pill per day (AOR=2.12, 95% CI 1.25– 3.58), using a clock as a reminder (AOR=2.51, 95% CI 1.3– 4.86), and having good male involvement (AOR=2.91, 95% CI 1.64– 5.16) were associated with good level of adherence for Option B plus ART treatment.Conclusion: Our study revealed that the level of good adherence is low compared with the national target. Therefore, addressing the low adherence of Option B plus ART requires a policy response, such as efforts to enhance male partner involvement and better service accessibility in Prevention of Mother-to-Child Transmission (PMTCT) program. Moreover, health care providers and policymakers need to maximaze their efforts on HIV positive pregnant and lactating mothers using a clock as a reminder.Keywords: adherence, Option B plus ART, Prevention of Mother-to-Child Transmission program; PMTCT, EthiopiaGebretsadik GGGebretnsae HFtwi MTesfahunegn ADove Medical Pressarticleadherenceoption b plus artpmtct programethiopia.Immunologic diseases. AllergyRC581-607ENHIV/AIDS: Research and Palliative Care, Vol Volume 12, Pp 687-695 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	adherence option b plus art pmtct program ethiopia. Immunologic diseases. Allergy RC581-607
spellingShingle	adherence option b plus art pmtct program ethiopia. Immunologic diseases. Allergy RC581-607 Gebretsadik GG Gebretnsae H Ftwi M Tesfahunegn A Alarm Clock-Based Reminder for Improving Low Adherence on Option B Plus Antiretroviral Therapy Among HIV Positive Pregnant and Lactating Mothers in Northern Ethiopia
description	Gebremedhin Gebreegziabher Gebretsadik,1 Hailay Gebretnsae,2 Mulu Ftwi,1 Afewerki Tesfahunegn3 1Department of Midwifery, College of Health Science, Adigrat University, Adigrat, Tigray, Ethiopia; 2Tigray Health Research Institute, Mekelle, Tigray, Ethiopia; 3Department of Epidemiology, College of Health Science, Mekelle University, Mekelle, Tigray, EthiopiaCorrespondence: Gebremedhin Gebreegziabher Gebretsadik Email gebremedhingebretsad@gmail.comBackground: Option B plus antiretroviral therapy (ART) is an approach used to eliminate new Human Immune Deficiency Virus (HIV) infections among infants. Considering the high adherence on Option B plus ART in HIV positive mothers is a crucial part in preventing mother-to-child transmission HIV. Therefore, this study was performed to assess the status of adherence and factors related to Option B plus ART.Methods: A cross-sectional study design was conducted in Eastern zone of Tigrai Region from January to February 2017. Data were collected by using pre-tested structured interviewer-administered questionnaire from 350 participants selected using simple random sampling. Descriptive and binary logistic regression was done during analysis.Results: The overall good adherence status of Option B plus ART among pregnant and lactating mothers was  67.3% [62.3– 72.3%]. Attending formal education (AOR=2.78, 95% CI 1.52– 5.07), traveling for < 1 hour to reach health facility (AOR=2.03, 95% CI 1.19– 3.44), (CD4) count < 350 cells/mm3 (AOR=2.3, 95% CI 1.33– 3.95), starting their Option B plus during pregnancy (AOR= 2.08, 95% CI 1.08– 3.97), taking one pill per day (AOR=2.12, 95% CI 1.25– 3.58), using a clock as a reminder (AOR=2.51, 95% CI 1.3– 4.86), and having good male involvement (AOR=2.91, 95% CI 1.64– 5.16) were associated with good level of adherence for Option B plus ART treatment.Conclusion: Our study revealed that the level of good adherence is low compared with the national target. Therefore, addressing the low adherence of Option B plus ART requires a policy response, such as efforts to enhance male partner involvement and better service accessibility in Prevention of Mother-to-Child Transmission (PMTCT) program. Moreover, health care providers and policymakers need to maximaze their efforts on HIV positive pregnant and lactating mothers using a clock as a reminder.Keywords: adherence, Option B plus ART, Prevention of Mother-to-Child Transmission program; PMTCT, Ethiopia
format	article
author	Gebretsadik GG Gebretnsae H Ftwi M Tesfahunegn A
author_facet	Gebretsadik GG Gebretnsae H Ftwi M Tesfahunegn A
author_sort	Gebretsadik GG
title	Alarm Clock-Based Reminder for Improving Low Adherence on Option B Plus Antiretroviral Therapy Among HIV Positive Pregnant and Lactating Mothers in Northern Ethiopia
title_short	Alarm Clock-Based Reminder for Improving Low Adherence on Option B Plus Antiretroviral Therapy Among HIV Positive Pregnant and Lactating Mothers in Northern Ethiopia
title_full	Alarm Clock-Based Reminder for Improving Low Adherence on Option B Plus Antiretroviral Therapy Among HIV Positive Pregnant and Lactating Mothers in Northern Ethiopia
title_fullStr	Alarm Clock-Based Reminder for Improving Low Adherence on Option B Plus Antiretroviral Therapy Among HIV Positive Pregnant and Lactating Mothers in Northern Ethiopia
title_full_unstemmed	Alarm Clock-Based Reminder for Improving Low Adherence on Option B Plus Antiretroviral Therapy Among HIV Positive Pregnant and Lactating Mothers in Northern Ethiopia
title_sort	alarm clock-based reminder for improving low adherence on option b plus antiretroviral therapy among hiv positive pregnant and lactating mothers in northern ethiopia
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/247ebf4d2a9b4606b4fbbead1b624224
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Alarm Clock-Based Reminder for Improving Low Adherence on Option B Plus Antiretroviral Therapy Among HIV Positive Pregnant and Lactating Mothers in Northern Ethiopia

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