Emergence of directional bias in tau deposition from axonal transport dynamics.
Defects in axonal transport may partly underpin the differences between the observed pathophysiology of Alzheimer's disease (AD) and that of other non-amyloidogenic tauopathies. Particularly, pathological tau variants may have molecular properties that dysregulate motor proteins responsible for...
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Autores principales: | Justin Torok, Pedro D Maia, Parul Verma, Christopher Mezias, Ashish Raj |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/24834eed861e4290ab95264ca3a273d1 |
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