Value of polymorphism of a gene of interleukin-17 (П-17а g-197a, il-17f his161arg) in a pathogenesis of the influenza IN children
The results of research of occurrence of genotypes of a polymorphic marker of a gene of interleukin-17 (IL-17А G-197A, IL-17F His161Arg) in 141 children at a influenza are presented in the article. It is established, that genotypes G/A of gene IL-17А G-197A and His/Arg gene IL-17F His161Arg act as f...
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Scientific Сentre for Family Health and Human Reproduction Problems
2013
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oai:doaj.org-article:2486d8f8695648deab9d058fe4b882342021-11-23T06:14:29ZValue of polymorphism of a gene of interleukin-17 (П-17а g-197a, il-17f his161arg) in a pathogenesis of the influenza IN children2541-94202587-9596https://doaj.org/article/2486d8f8695648deab9d058fe4b882342013-11-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1677https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The results of research of occurrence of genotypes of a polymorphic marker of a gene of interleukin-17 (IL-17А G-197A, IL-17F His161Arg) in 141 children at a influenza are presented in the article. It is established, that genotypes G/A of gene IL-17А G-197A and His/Arg gene IL-17F His161Arg act as factors of protection in children at a seasonal influenza. And at a influenza A H1N1/v genotypes G/A of gene IL-17А G-197A and His/Arg gene IL-17F His161Arg are associated with risk of occurrence of a disease. Serious forms of a pandemic influenza are accompanied by frequent revealing of allele Arg and more rare - of His gene IL-17F His161Arg in comparison with not serious forms of a influenza A H1N1/v.N. A. MiromanovaScientific Сentre for Family Health and Human Reproduction ProblemsarticleinfluenzachildrenpolymorphisminterleukinScienceQRUActa Biomedica Scientifica, Vol 0, Iss 6, Pp 33-37 (2013) |
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influenza children polymorphism interleukin Science Q |
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influenza children polymorphism interleukin Science Q N. A. Miromanova Value of polymorphism of a gene of interleukin-17 (П-17а g-197a, il-17f his161arg) in a pathogenesis of the influenza IN children |
description |
The results of research of occurrence of genotypes of a polymorphic marker of a gene of interleukin-17 (IL-17А G-197A, IL-17F His161Arg) in 141 children at a influenza are presented in the article. It is established, that genotypes G/A of gene IL-17А G-197A and His/Arg gene IL-17F His161Arg act as factors of protection in children at a seasonal influenza. And at a influenza A H1N1/v genotypes G/A of gene IL-17А G-197A and His/Arg gene IL-17F His161Arg are associated with risk of occurrence of a disease. Serious forms of a pandemic influenza are accompanied by frequent revealing of allele Arg and more rare - of His gene IL-17F His161Arg in comparison with not serious forms of a influenza A H1N1/v. |
format |
article |
author |
N. A. Miromanova |
author_facet |
N. A. Miromanova |
author_sort |
N. A. Miromanova |
title |
Value of polymorphism of a gene of interleukin-17 (П-17а g-197a, il-17f his161arg) in a pathogenesis of the influenza IN children |
title_short |
Value of polymorphism of a gene of interleukin-17 (П-17а g-197a, il-17f his161arg) in a pathogenesis of the influenza IN children |
title_full |
Value of polymorphism of a gene of interleukin-17 (П-17а g-197a, il-17f his161arg) in a pathogenesis of the influenza IN children |
title_fullStr |
Value of polymorphism of a gene of interleukin-17 (П-17а g-197a, il-17f his161arg) in a pathogenesis of the influenza IN children |
title_full_unstemmed |
Value of polymorphism of a gene of interleukin-17 (П-17а g-197a, il-17f his161arg) in a pathogenesis of the influenza IN children |
title_sort |
value of polymorphism of a gene of interleukin-17 (п-17а g-197a, il-17f his161arg) in a pathogenesis of the influenza in children |
publisher |
Scientific Сentre for Family Health and Human Reproduction Problems |
publishDate |
2013 |
url |
https://doaj.org/article/2486d8f8695648deab9d058fe4b88234 |
work_keys_str_mv |
AT namiromanova valueofpolymorphismofageneofinterleukin17p17ag197ail17fhis161arginapathogenesisoftheinfluenzainchildren |
_version_ |
1718417119971901440 |