Anti-inflammatory and anti-fibrotic effects of modafinil in nonalcoholic liver disease

Small- and intermediate-conductance Ca2+-activated K+ channels, KCa2.3 and KCa3.1, are involved in cellular signaling processes associated with inflammation and fibrosis. KCa2.3 and KCa3.1 are upregulated by proinflammatory cytokines and profibrotic growth factors. Cyclic AMP, which downregulates KC...

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Autores principales: Shinkyu Choi, Ji Aee Kim, Haiyan Li, Seong-Eun Jo, Huisu Lee, Tae Hun Kim, Minje Kim, Seong-Jin Kim, Suk Hyo Suh
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/248c5d63c5e548cd81023d099535ae43
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