Association between Serum 25-Hydroxyvitamin D Level and Stroke Risk: An Analysis Based on the National Health and Nutrition Examination Survey

Background. To analyze the association between serum 25-hydroxyvitamin D level (25(OH)D) and stroke risk based on the National Health and Nutrition Examination Survey (NHANES). Methods. Between 2007 and 2018, the baseline information of participants from NHNES was collected. Univariate analysis was...

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Autores principales:	Lan Wang, Shu Li, G. H. Anuja Sanika, Jinsheng Zhao, Hui Zhang, Lin Zhao, Wenfeng Wang
Formato:	article
Lenguaje:	EN
Publicado:	Hindawi Limited 2021
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
Acceso en línea:	https://doaj.org/article/248d7663328445daa78ef03055f31bf1
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spelling	oai:doaj.org-article:248d7663328445daa78ef03055f31bf12021-11-08T02:35:29ZAssociation between Serum 25-Hydroxyvitamin D Level and Stroke Risk: An Analysis Based on the National Health and Nutrition Examination Survey1875-858410.1155/2021/5457881https://doaj.org/article/248d7663328445daa78ef03055f31bf12021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/5457881https://doaj.org/toc/1875-8584Background. To analyze the association between serum 25-hydroxyvitamin D level (25(OH)D) and stroke risk based on the National Health and Nutrition Examination Survey (NHANES). Methods. Between 2007 and 2018, the baseline information of participants from NHNES was collected. Univariate analysis was used to identify the covariates. Multivariate logistic regression model was used to analyze the association between serum 25(OH)D level and the stroke risk. Results. Of the 8,523 participants, there were 310 participants with stroke and 8,213 participants without stroke. The multivariate logistic analysis showed that serum 25(OH)D deficiency (odds ratio (OR): 1.993, 95% confidence intervals (CI): 1.141-3.481, and P=0.012) was the significant risk factors for stroke. Subgroup analysis showed that non-Hispanic whites with serum 25(OH)D deficiency (OR: 2.501, 95% CI: 1.094-5.720, and P=0.001) and insufficiency (OR: 1.853, 95% CI: 1.170-2.934, and P=0.006) were associated with a higher risk of stroke than those with normal 25(OH)D levels. Conclusions. Serum 25(OH)D deficiency may be associated with an increased risk of stroke.Lan WangShu LiG. H. Anuja SanikaJinsheng ZhaoHui ZhangLin ZhaoWenfeng WangHindawi LimitedarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571ENBehavioural Neurology, Vol 2021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Lan Wang Shu Li G. H. Anuja Sanika Jinsheng Zhao Hui Zhang Lin Zhao Wenfeng Wang Association between Serum 25-Hydroxyvitamin D Level and Stroke Risk: An Analysis Based on the National Health and Nutrition Examination Survey
description	Background. To analyze the association between serum 25-hydroxyvitamin D level (25(OH)D) and stroke risk based on the National Health and Nutrition Examination Survey (NHANES). Methods. Between 2007 and 2018, the baseline information of participants from NHNES was collected. Univariate analysis was used to identify the covariates. Multivariate logistic regression model was used to analyze the association between serum 25(OH)D level and the stroke risk. Results. Of the 8,523 participants, there were 310 participants with stroke and 8,213 participants without stroke. The multivariate logistic analysis showed that serum 25(OH)D deficiency (odds ratio (OR): 1.993, 95% confidence intervals (CI): 1.141-3.481, and P=0.012) was the significant risk factors for stroke. Subgroup analysis showed that non-Hispanic whites with serum 25(OH)D deficiency (OR: 2.501, 95% CI: 1.094-5.720, and P=0.001) and insufficiency (OR: 1.853, 95% CI: 1.170-2.934, and P=0.006) were associated with a higher risk of stroke than those with normal 25(OH)D levels. Conclusions. Serum 25(OH)D deficiency may be associated with an increased risk of stroke.
format	article
author	Lan Wang Shu Li G. H. Anuja Sanika Jinsheng Zhao Hui Zhang Lin Zhao Wenfeng Wang
author_facet	Lan Wang Shu Li G. H. Anuja Sanika Jinsheng Zhao Hui Zhang Lin Zhao Wenfeng Wang
author_sort	Lan Wang
title	Association between Serum 25-Hydroxyvitamin D Level and Stroke Risk: An Analysis Based on the National Health and Nutrition Examination Survey
title_short	Association between Serum 25-Hydroxyvitamin D Level and Stroke Risk: An Analysis Based on the National Health and Nutrition Examination Survey
title_full	Association between Serum 25-Hydroxyvitamin D Level and Stroke Risk: An Analysis Based on the National Health and Nutrition Examination Survey
title_fullStr	Association between Serum 25-Hydroxyvitamin D Level and Stroke Risk: An Analysis Based on the National Health and Nutrition Examination Survey
title_full_unstemmed	Association between Serum 25-Hydroxyvitamin D Level and Stroke Risk: An Analysis Based on the National Health and Nutrition Examination Survey
title_sort	association between serum 25-hydroxyvitamin d level and stroke risk: an analysis based on the national health and nutrition examination survey
publisher	Hindawi Limited
publishDate	2021
url	https://doaj.org/article/248d7663328445daa78ef03055f31bf1
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Association between Serum 25-Hydroxyvitamin D Level and Stroke Risk: An Analysis Based on the National Health and Nutrition Examination Survey

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