Antiangiogenic properties of nanoparticles: a systematic review

Brhaish Ali Saeed,1 Vuanghao Lim,1 Nor Adlin Yusof,1 Kang Zi Khor,1 Heshu Sulaiman Rahman2,3, Nozlena Abdul Samad1  1Integrative Medicine Cluster, Advanced Medical and Dental Institute, SAINS@ Bertam, Universiti Sains Malaysia, Kepala Batas 13200, Pulau Pinang, Malaysia; 2Departmen...

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Autores principales:	Saeed BA, Lim V, Yusof NA, Khor KZ, Rahman HS, Abdul Samad N
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2019
Materias:	Nanoparticles angiogenesis anti-angiogenesis size shape toxicity Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/249bcc2686a942f1a132481deb12ed3f
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spelling	oai:doaj.org-article:249bcc2686a942f1a132481deb12ed3f2021-12-02T06:36:31ZAntiangiogenic properties of nanoparticles: a systematic review1178-2013https://doaj.org/article/249bcc2686a942f1a132481deb12ed3f2019-07-01T00:00:00Zhttps://www.dovepress.com/antiangiogenic-properties-of-nanoparticles-a-systematic-review-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013Brhaish Ali Saeed,1 Vuanghao Lim,1 Nor Adlin Yusof,1 Kang Zi Khor,1 Heshu Sulaiman Rahman2,3, Nozlena Abdul Samad1  1Integrative Medicine Cluster, Advanced Medical and Dental Institute, SAINS@ Bertam, Universiti Sains Malaysia, Kepala Batas 13200, Pulau Pinang, Malaysia; 2Department of Clinic and Internal Medicine, College of Veterinary Medicine, University of Sulaimani, Sulaymaniyah City 46001, Republic of Iraq; 3Department of Medical Laboratory Sciences, College of Health Sciences, Komar University of Science and Technology, Sarchinar District, Republic of IraqAbstract: Nanoparticles appear to be one of the most promising agents that offer efficacy in angiogenesis-related disease therapy. The objective of this research is to systematically review studies that have probed into the effect of nanoparticles on angiogenesis. Selected inclusion criteria were used to extract articles, references that were cited in the initial search were sought to identify more potential articles, and articles that did not meet the inclusion criteria and duplicates were discarded. The spherical shape was shown to be the most common shape employed to investigate the role of nanoparticles in angiogenesis therapy. The size of nanoparticles appears to play a crucial role for efficacy on angiogenesis, in which 20 nm emerged as the preferred size. Gold nanoparticles exhibit the most promise as an antiangiogenesis agent, and the toxicity was adjustable based on the dosages applied.Keywords: nanoparticles, angiogenesis, antiangiogenesis, size, shape, toxicitySaeed BALim VYusof NAKhor KZRahman HSAbdul Samad NDove Medical PressarticleNanoparticlesangiogenesisanti-angiogenesissizeshapetoxicityMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol Volume 14, Pp 5135-5146 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Nanoparticles angiogenesis anti-angiogenesis size shape toxicity Medicine (General) R5-920
spellingShingle	Nanoparticles angiogenesis anti-angiogenesis size shape toxicity Medicine (General) R5-920 Saeed BA Lim V Yusof NA Khor KZ Rahman HS Abdul Samad N Antiangiogenic properties of nanoparticles: a systematic review
description	Brhaish Ali Saeed,1 Vuanghao Lim,1 Nor Adlin Yusof,1 Kang Zi Khor,1 Heshu Sulaiman Rahman2,3, Nozlena Abdul Samad1  1Integrative Medicine Cluster, Advanced Medical and Dental Institute, SAINS@ Bertam, Universiti Sains Malaysia, Kepala Batas 13200, Pulau Pinang, Malaysia; 2Department of Clinic and Internal Medicine, College of Veterinary Medicine, University of Sulaimani, Sulaymaniyah City 46001, Republic of Iraq; 3Department of Medical Laboratory Sciences, College of Health Sciences, Komar University of Science and Technology, Sarchinar District, Republic of IraqAbstract: Nanoparticles appear to be one of the most promising agents that offer efficacy in angiogenesis-related disease therapy. The objective of this research is to systematically review studies that have probed into the effect of nanoparticles on angiogenesis. Selected inclusion criteria were used to extract articles, references that were cited in the initial search were sought to identify more potential articles, and articles that did not meet the inclusion criteria and duplicates were discarded. The spherical shape was shown to be the most common shape employed to investigate the role of nanoparticles in angiogenesis therapy. The size of nanoparticles appears to play a crucial role for efficacy on angiogenesis, in which 20 nm emerged as the preferred size. Gold nanoparticles exhibit the most promise as an antiangiogenesis agent, and the toxicity was adjustable based on the dosages applied.Keywords: nanoparticles, angiogenesis, antiangiogenesis, size, shape, toxicity
format	article
author	Saeed BA Lim V Yusof NA Khor KZ Rahman HS Abdul Samad N
author_facet	Saeed BA Lim V Yusof NA Khor KZ Rahman HS Abdul Samad N
author_sort	Saeed BA
title	Antiangiogenic properties of nanoparticles: a systematic review
title_short	Antiangiogenic properties of nanoparticles: a systematic review
title_full	Antiangiogenic properties of nanoparticles: a systematic review
title_fullStr	Antiangiogenic properties of nanoparticles: a systematic review
title_full_unstemmed	Antiangiogenic properties of nanoparticles: a systematic review
title_sort	antiangiogenic properties of nanoparticles: a systematic review
publisher	Dove Medical Press
publishDate	2019
url	https://doaj.org/article/249bcc2686a942f1a132481deb12ed3f
work_keys_str_mv	AT saeedba antiangiogenicpropertiesofnanoparticlesasystematicreview AT limv antiangiogenicpropertiesofnanoparticlesasystematicreview AT yusofna antiangiogenicpropertiesofnanoparticlesasystematicreview AT khorkz antiangiogenicpropertiesofnanoparticlesasystematicreview AT rahmanhs antiangiogenicpropertiesofnanoparticlesasystematicreview AT abdulsamadn antiangiogenicpropertiesofnanoparticlesasystematicreview
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Antiangiogenic properties of nanoparticles: a systematic review

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