Acetylation of PAX7 controls muscle stem cell self-renewal and differentiation potential in mice

The acetyltransferase MYST1 stimulated by acetyl-CoA, and the deacetylase SIRT2 stimulated by NAD+, regulate PAX7 acetylation in muscle stem cells, which in turn, regulates stem cell self-renewal and regeneration following injury in mouse skeletal muscle.

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Autores principales:	Marie-Claude Sincennes, Caroline E. Brun, Alexander Y. T. Lin, Tabitha Rosembert, David Datzkiw, John Saber, Hong Ming, Yoh-ichi Kawabe, Michael A. Rudnicki
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/24a0e0653321457e90cacbe83a5277e7
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spelling	oai:doaj.org-article:24a0e0653321457e90cacbe83a5277e72021-12-02T17:51:19ZAcetylation of PAX7 controls muscle stem cell self-renewal and differentiation potential in mice10.1038/s41467-021-23577-z2041-1723https://doaj.org/article/24a0e0653321457e90cacbe83a5277e72021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23577-zhttps://doaj.org/toc/2041-1723The acetyltransferase MYST1 stimulated by acetyl-CoA, and the deacetylase SIRT2 stimulated by NAD+, regulate PAX7 acetylation in muscle stem cells, which in turn, regulates stem cell self-renewal and regeneration following injury in mouse skeletal muscle.Marie-Claude SincennesCaroline E. BrunAlexander Y. T. LinTabitha RosembertDavid DatzkiwJohn SaberHong MingYoh-ichi KawabeMichael A. RudnickiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Marie-Claude Sincennes Caroline E. Brun Alexander Y. T. Lin Tabitha Rosembert David Datzkiw John Saber Hong Ming Yoh-ichi Kawabe Michael A. Rudnicki Acetylation of PAX7 controls muscle stem cell self-renewal and differentiation potential in mice
description	The acetyltransferase MYST1 stimulated by acetyl-CoA, and the deacetylase SIRT2 stimulated by NAD+, regulate PAX7 acetylation in muscle stem cells, which in turn, regulates stem cell self-renewal and regeneration following injury in mouse skeletal muscle.
format	article
author	Marie-Claude Sincennes Caroline E. Brun Alexander Y. T. Lin Tabitha Rosembert David Datzkiw John Saber Hong Ming Yoh-ichi Kawabe Michael A. Rudnicki
author_facet	Marie-Claude Sincennes Caroline E. Brun Alexander Y. T. Lin Tabitha Rosembert David Datzkiw John Saber Hong Ming Yoh-ichi Kawabe Michael A. Rudnicki
author_sort	Marie-Claude Sincennes
title	Acetylation of PAX7 controls muscle stem cell self-renewal and differentiation potential in mice
title_short	Acetylation of PAX7 controls muscle stem cell self-renewal and differentiation potential in mice
title_full	Acetylation of PAX7 controls muscle stem cell self-renewal and differentiation potential in mice
title_fullStr	Acetylation of PAX7 controls muscle stem cell self-renewal and differentiation potential in mice
title_full_unstemmed	Acetylation of PAX7 controls muscle stem cell self-renewal and differentiation potential in mice
title_sort	acetylation of pax7 controls muscle stem cell self-renewal and differentiation potential in mice
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/24a0e0653321457e90cacbe83a5277e7
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Acetylation of PAX7 controls muscle stem cell self-renewal and differentiation potential in mice

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