Relaxation capacity of cartilage is a critical factor in rate- and integrity-dependent fracture

Relaxation capacity of cartilage is a critical factor in rate- and integrity-dependent fracture

Abstract Articular cartilage heals poorly but experiences mechanically induced damage across a broad range of loading rates and matrix integrity. Because loading rates and matrix integrity affect cartilage mechanical responses due to poroviscoelastic relaxation mechanisms, their effects on cartilage...

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Autores principales: G. Han, U. Chowdhury, M. Eriten, C. R. Henak
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
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Science
Q
Acceso en línea:https://doaj.org/article/24aaee603d1840d4a7ddee04333df811
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spelling oai:doaj.org-article:24aaee603d1840d4a7ddee04333df8112021-12-02T16:49:12ZRelaxation capacity of cartilage is a critical factor in rate- and integrity-dependent fracture10.1038/s41598-021-88942-w2045-2322https://doaj.org/article/24aaee603d1840d4a7ddee04333df8112021-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-88942-whttps://doaj.org/toc/2045-2322Abstract Articular cartilage heals poorly but experiences mechanically induced damage across a broad range of loading rates and matrix integrity. Because loading rates and matrix integrity affect cartilage mechanical responses due to poroviscoelastic relaxation mechanisms, their effects on cartilage failure are important for assessing and preventing failure. This paper investigated rate- and integrity-dependent crack nucleation in cartilage from pre- to post-relaxation timescales. Rate-dependent crack nucleation and relaxation responses were obtained as a function of matrix integrity through microindentation. Total work for crack nucleation increased with decreased matrix integrity, and with decreased loading rates. Critical energy release rate of intact cartilage was estimated as 2.39 ± 1.39 to 2.48 ± 1.26 kJ m−2 in a pre-relaxation timescale. These findings showed that crack nucleation is delayed when cartilage can accommodate localized loading through poroviscoelastic relaxation mechanisms before fracture at a given loading rate and integrity state.G. HanU. ChowdhuryM. EritenC. R. HenakNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
G. Han
U. Chowdhury
M. Eriten
C. R. Henak
Relaxation capacity of cartilage is a critical factor in rate- and integrity-dependent fracture
description Abstract Articular cartilage heals poorly but experiences mechanically induced damage across a broad range of loading rates and matrix integrity. Because loading rates and matrix integrity affect cartilage mechanical responses due to poroviscoelastic relaxation mechanisms, their effects on cartilage failure are important for assessing and preventing failure. This paper investigated rate- and integrity-dependent crack nucleation in cartilage from pre- to post-relaxation timescales. Rate-dependent crack nucleation and relaxation responses were obtained as a function of matrix integrity through microindentation. Total work for crack nucleation increased with decreased matrix integrity, and with decreased loading rates. Critical energy release rate of intact cartilage was estimated as 2.39 ± 1.39 to 2.48 ± 1.26 kJ m−2 in a pre-relaxation timescale. These findings showed that crack nucleation is delayed when cartilage can accommodate localized loading through poroviscoelastic relaxation mechanisms before fracture at a given loading rate and integrity state.
format article
author G. Han
U. Chowdhury
M. Eriten
C. R. Henak
author_facet G. Han
U. Chowdhury
M. Eriten
C. R. Henak
author_sort G. Han
title Relaxation capacity of cartilage is a critical factor in rate- and integrity-dependent fracture
title_short Relaxation capacity of cartilage is a critical factor in rate- and integrity-dependent fracture
title_full Relaxation capacity of cartilage is a critical factor in rate- and integrity-dependent fracture
title_fullStr Relaxation capacity of cartilage is a critical factor in rate- and integrity-dependent fracture
title_full_unstemmed Relaxation capacity of cartilage is a critical factor in rate- and integrity-dependent fracture
title_sort relaxation capacity of cartilage is a critical factor in rate- and integrity-dependent fracture
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/24aaee603d1840d4a7ddee04333df811
work_keys_str_mv AT ghan relaxationcapacityofcartilageisacriticalfactorinrateandintegritydependentfracture
AT uchowdhury relaxationcapacityofcartilageisacriticalfactorinrateandintegritydependentfracture
AT meriten relaxationcapacityofcartilageisacriticalfactorinrateandintegritydependentfracture
AT crhenak relaxationcapacityofcartilageisacriticalfactorinrateandintegritydependentfracture
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