Molecular mechanisms of Bdp1 in TFIIIB assembly and RNA polymerase III transcription initiation

Transcription initiation by RNA polymerase III requires TFIIIB, a complex formed by Brf1/Brf2, TBP and Bdp1. Here, the authors describe the crystal structure of a Brf2-TBP-Bdp1 complex bound to a DNA promoter and characterize the role of Bdp1 in TFIIIB assembly and pre-initiation complex formation.

Guardado en:

Detalles Bibliográficos
Autores principales:	Jerome Gouge, Nicolas Guthertz, Kevin Kramm, Oleksandr Dergai, Guillermo Abascal-Palacios, Karishma Satia, Pascal Cousin, Nouria Hernandez, Dina Grohmann, Alessandro Vannini
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/24b5aabdb8694c1e890901d3aeef0ee9
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:24b5aabdb8694c1e890901d3aeef0ee9
record_format	dspace
spelling	oai:doaj.org-article:24b5aabdb8694c1e890901d3aeef0ee92021-12-02T10:48:18ZMolecular mechanisms of Bdp1 in TFIIIB assembly and RNA polymerase III transcription initiation10.1038/s41467-017-00126-12041-1723https://doaj.org/article/24b5aabdb8694c1e890901d3aeef0ee92017-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00126-1https://doaj.org/toc/2041-1723Transcription initiation by RNA polymerase III requires TFIIIB, a complex formed by Brf1/Brf2, TBP and Bdp1. Here, the authors describe the crystal structure of a Brf2-TBP-Bdp1 complex bound to a DNA promoter and characterize the role of Bdp1 in TFIIIB assembly and pre-initiation complex formation.Jerome GougeNicolas GuthertzKevin KrammOleksandr DergaiGuillermo Abascal-PalaciosKarishma SatiaPascal CousinNouria HernandezDina GrohmannAlessandro VanniniNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jerome Gouge Nicolas Guthertz Kevin Kramm Oleksandr Dergai Guillermo Abascal-Palacios Karishma Satia Pascal Cousin Nouria Hernandez Dina Grohmann Alessandro Vannini Molecular mechanisms of Bdp1 in TFIIIB assembly and RNA polymerase III transcription initiation
description	Transcription initiation by RNA polymerase III requires TFIIIB, a complex formed by Brf1/Brf2, TBP and Bdp1. Here, the authors describe the crystal structure of a Brf2-TBP-Bdp1 complex bound to a DNA promoter and characterize the role of Bdp1 in TFIIIB assembly and pre-initiation complex formation.
format	article
author	Jerome Gouge Nicolas Guthertz Kevin Kramm Oleksandr Dergai Guillermo Abascal-Palacios Karishma Satia Pascal Cousin Nouria Hernandez Dina Grohmann Alessandro Vannini
author_facet	Jerome Gouge Nicolas Guthertz Kevin Kramm Oleksandr Dergai Guillermo Abascal-Palacios Karishma Satia Pascal Cousin Nouria Hernandez Dina Grohmann Alessandro Vannini
author_sort	Jerome Gouge
title	Molecular mechanisms of Bdp1 in TFIIIB assembly and RNA polymerase III transcription initiation
title_short	Molecular mechanisms of Bdp1 in TFIIIB assembly and RNA polymerase III transcription initiation
title_full	Molecular mechanisms of Bdp1 in TFIIIB assembly and RNA polymerase III transcription initiation
title_fullStr	Molecular mechanisms of Bdp1 in TFIIIB assembly and RNA polymerase III transcription initiation
title_full_unstemmed	Molecular mechanisms of Bdp1 in TFIIIB assembly and RNA polymerase III transcription initiation
title_sort	molecular mechanisms of bdp1 in tfiiib assembly and rna polymerase iii transcription initiation
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/24b5aabdb8694c1e890901d3aeef0ee9
work_keys_str_mv	AT jeromegouge molecularmechanismsofbdp1intfiiibassemblyandrnapolymeraseiiitranscriptioninitiation AT nicolasguthertz molecularmechanismsofbdp1intfiiibassemblyandrnapolymeraseiiitranscriptioninitiation AT kevinkramm molecularmechanismsofbdp1intfiiibassemblyandrnapolymeraseiiitranscriptioninitiation AT oleksandrdergai molecularmechanismsofbdp1intfiiibassemblyandrnapolymeraseiiitranscriptioninitiation AT guillermoabascalpalacios molecularmechanismsofbdp1intfiiibassemblyandrnapolymeraseiiitranscriptioninitiation AT karishmasatia molecularmechanismsofbdp1intfiiibassemblyandrnapolymeraseiiitranscriptioninitiation AT pascalcousin molecularmechanismsofbdp1intfiiibassemblyandrnapolymeraseiiitranscriptioninitiation AT nouriahernandez molecularmechanismsofbdp1intfiiibassemblyandrnapolymeraseiiitranscriptioninitiation AT dinagrohmann molecularmechanismsofbdp1intfiiibassemblyandrnapolymeraseiiitranscriptioninitiation AT alessandrovannini molecularmechanismsofbdp1intfiiibassemblyandrnapolymeraseiiitranscriptioninitiation
_version_	1718396636500066304

Molecular mechanisms of Bdp1 in TFIIIB assembly and RNA polymerase III transcription initiation

Ejemplares similares