Intestinal barrier dysfunction develops at the onset of experimental autoimmune encephalomyelitis, and can be induced by adoptive transfer of auto-reactive T cells.
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system with a pathogenesis involving a dysfunctional blood-brain barrier and myelin-specific, autoreactive T cells. Although the commensal microbiota seems to affect its pathogenesis, regulation of the int...
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Main Authors: | Mehrnaz Nouri, Anders Bredberg, Björn Weström, Shahram Lavasani |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2014
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Online Access: | https://doaj.org/article/24b7572cb6cf4f0790a348176ab2c54a |
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