A randomized controlled trial comparing functional outcomes for navigated kinematically aligned total knee arthroplasty versus navigated mechanically aligned total knee arthroplasty: the MaKKRO trial

Aims: Nearly 99,000 total knee arthroplasties (TKAs) are performed in UK annually. Despite plenty of research, the satisfaction rate of this surgery is around 80%. One of the important intraoperative factors affecting the outcome is alignment. The relationship between joint obliquity and functional...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Vilas Narayan Sadekar, Sandeep Datir, Victoria Allgar, Hemant Sharma
Formato:	article
Lenguaje:	EN
Publicado:	The British Editorial Society of Bone & Joint Surgery 2021
Materias:	arthroplasty mechanical kinematic alignment protocol navigation joint line randomized controlled trial functional outcomes total knee arthroplasties (tkas) knee injury and osteoarthritis outcome score knee arthroplasties visual analogue scale oxford knee score forgotten joint score sf-12 short form health survey Orthopedic surgery RD701-811
Acceso en línea:	https://doaj.org/article/24bfa827e66449d492930ce87fe42b0e
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:24bfa827e66449d492930ce87fe42b0e
record_format	dspace
spelling	oai:doaj.org-article:24bfa827e66449d492930ce87fe42b0e2021-12-01T18:44:47ZA randomized controlled trial comparing functional outcomes for navigated kinematically aligned total knee arthroplasty versus navigated mechanically aligned total knee arthroplasty: the MaKKRO trial2633-146210.1302/2633-1462.211.BJO-2021-0094.R1https://doaj.org/article/24bfa827e66449d492930ce87fe42b0e2021-11-01T00:00:00Zhttps://online.boneandjoint.org.uk/doi/epdf/10.1302/2633-1462.211.BJO-2021-0094.R1https://doaj.org/toc/2633-1462Aims: Nearly 99,000 total knee arthroplasties (TKAs) are performed in UK annually. Despite plenty of research, the satisfaction rate of this surgery is around 80%. One of the important intraoperative factors affecting the outcome is alignment. The relationship between joint obliquity and functional outcomes is not well understood. Therefore, a study is required to investigate and compare the effects of two types of alignment (mechanical and kinematic) on functional outcomes and range of motion. Methods: The aim of the study is to compare navigated kinematically aligned TKAs (KA TKAs) with navigated mechanically aligned TKA (MA TKA) in terms of function and ROM. We aim to recruit a total of 96 patients in the trial. The patients will be recruited from clinics of various consultants working in the trust after screening them for eligibility criteria and obtaining their informed consent to participate in this study. Randomization will be done prior to surgery by a software. The primary outcome measure will be the Knee injury and Osteoarthritis Outcome Score The secondary outcome measures include Oxford Knee Score, ROM, EuroQol five-dimension questionnaire, EuroQol visual analogue scale, 12-Item Short-Form Health Survey (SF-12), and Forgotten Joint Score. The scores will be calculated preoperatively and then at six weeks, six months, and one year after surgery. The scores will undergo a statistical analysis. Discussion: There is no clear evidence on the best alignment for a knee arthroplasty. This randomized controlled trial will test the null hypothesis that navigated KA TKAs do not perform better than navigated MA TKAs. Cite this article: Bone Jt Open 2021;2(11):945–950.Vilas Narayan SadekarSandeep DatirVictoria AllgarHemant SharmaThe British Editorial Society of Bone & Joint Surgeryarticlearthroplastymechanicalkinematicalignmentprotocolnavigationjoint linerandomized controlled trialfunctional outcomestotal knee arthroplasties (tkas)knee injury and osteoarthritis outcome scoreknee arthroplastiesvisual analogue scaleoxford knee scoreforgotten joint scoresf-12short form health surveyOrthopedic surgeryRD701-811ENBone & Joint Open, Vol 2, Iss 11, Pp 945-950 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	arthroplasty mechanical kinematic alignment protocol navigation joint line randomized controlled trial functional outcomes total knee arthroplasties (tkas) knee injury and osteoarthritis outcome score knee arthroplasties visual analogue scale oxford knee score forgotten joint score sf-12 short form health survey Orthopedic surgery RD701-811
spellingShingle	arthroplasty mechanical kinematic alignment protocol navigation joint line randomized controlled trial functional outcomes total knee arthroplasties (tkas) knee injury and osteoarthritis outcome score knee arthroplasties visual analogue scale oxford knee score forgotten joint score sf-12 short form health survey Orthopedic surgery RD701-811 Vilas Narayan Sadekar Sandeep Datir Victoria Allgar Hemant Sharma A randomized controlled trial comparing functional outcomes for navigated kinematically aligned total knee arthroplasty versus navigated mechanically aligned total knee arthroplasty: the MaKKRO trial
description	Aims: Nearly 99,000 total knee arthroplasties (TKAs) are performed in UK annually. Despite plenty of research, the satisfaction rate of this surgery is around 80%. One of the important intraoperative factors affecting the outcome is alignment. The relationship between joint obliquity and functional outcomes is not well understood. Therefore, a study is required to investigate and compare the effects of two types of alignment (mechanical and kinematic) on functional outcomes and range of motion. Methods: The aim of the study is to compare navigated kinematically aligned TKAs (KA TKAs) with navigated mechanically aligned TKA (MA TKA) in terms of function and ROM. We aim to recruit a total of 96 patients in the trial. The patients will be recruited from clinics of various consultants working in the trust after screening them for eligibility criteria and obtaining their informed consent to participate in this study. Randomization will be done prior to surgery by a software. The primary outcome measure will be the Knee injury and Osteoarthritis Outcome Score The secondary outcome measures include Oxford Knee Score, ROM, EuroQol five-dimension questionnaire, EuroQol visual analogue scale, 12-Item Short-Form Health Survey (SF-12), and Forgotten Joint Score. The scores will be calculated preoperatively and then at six weeks, six months, and one year after surgery. The scores will undergo a statistical analysis. Discussion: There is no clear evidence on the best alignment for a knee arthroplasty. This randomized controlled trial will test the null hypothesis that navigated KA TKAs do not perform better than navigated MA TKAs. Cite this article: Bone Jt Open 2021;2(11):945–950.
format	article
author	Vilas Narayan Sadekar Sandeep Datir Victoria Allgar Hemant Sharma
author_facet	Vilas Narayan Sadekar Sandeep Datir Victoria Allgar Hemant Sharma
author_sort	Vilas Narayan Sadekar
title	A randomized controlled trial comparing functional outcomes for navigated kinematically aligned total knee arthroplasty versus navigated mechanically aligned total knee arthroplasty: the MaKKRO trial
title_short	A randomized controlled trial comparing functional outcomes for navigated kinematically aligned total knee arthroplasty versus navigated mechanically aligned total knee arthroplasty: the MaKKRO trial
title_full	A randomized controlled trial comparing functional outcomes for navigated kinematically aligned total knee arthroplasty versus navigated mechanically aligned total knee arthroplasty: the MaKKRO trial
title_fullStr	A randomized controlled trial comparing functional outcomes for navigated kinematically aligned total knee arthroplasty versus navigated mechanically aligned total knee arthroplasty: the MaKKRO trial
title_full_unstemmed	A randomized controlled trial comparing functional outcomes for navigated kinematically aligned total knee arthroplasty versus navigated mechanically aligned total knee arthroplasty: the MaKKRO trial
title_sort	randomized controlled trial comparing functional outcomes for navigated kinematically aligned total knee arthroplasty versus navigated mechanically aligned total knee arthroplasty: the makkro trial
publisher	The British Editorial Society of Bone & Joint Surgery
publishDate	2021
url	https://doaj.org/article/24bfa827e66449d492930ce87fe42b0e
work_keys_str_mv	AT vilasnarayansadekar arandomizedcontrolledtrialcomparingfunctionaloutcomesfornavigatedkinematicallyalignedtotalkneearthroplastyversusnavigatedmechanicallyalignedtotalkneearthroplastythemakkrotrial AT sandeepdatir arandomizedcontrolledtrialcomparingfunctionaloutcomesfornavigatedkinematicallyalignedtotalkneearthroplastyversusnavigatedmechanicallyalignedtotalkneearthroplastythemakkrotrial AT victoriaallgar arandomizedcontrolledtrialcomparingfunctionaloutcomesfornavigatedkinematicallyalignedtotalkneearthroplastyversusnavigatedmechanicallyalignedtotalkneearthroplastythemakkrotrial AT hemantsharma arandomizedcontrolledtrialcomparingfunctionaloutcomesfornavigatedkinematicallyalignedtotalkneearthroplastyversusnavigatedmechanicallyalignedtotalkneearthroplastythemakkrotrial AT vilasnarayansadekar randomizedcontrolledtrialcomparingfunctionaloutcomesfornavigatedkinematicallyalignedtotalkneearthroplastyversusnavigatedmechanicallyalignedtotalkneearthroplastythemakkrotrial AT sandeepdatir randomizedcontrolledtrialcomparingfunctionaloutcomesfornavigatedkinematicallyalignedtotalkneearthroplastyversusnavigatedmechanicallyalignedtotalkneearthroplastythemakkrotrial AT victoriaallgar randomizedcontrolledtrialcomparingfunctionaloutcomesfornavigatedkinematicallyalignedtotalkneearthroplastyversusnavigatedmechanicallyalignedtotalkneearthroplastythemakkrotrial AT hemantsharma randomizedcontrolledtrialcomparingfunctionaloutcomesfornavigatedkinematicallyalignedtotalkneearthroplastyversusnavigatedmechanicallyalignedtotalkneearthroplastythemakkrotrial
_version_	1718404679792066560

A randomized controlled trial comparing functional outcomes for navigated kinematically aligned total knee arthroplasty versus navigated mechanically aligned total knee arthroplasty: the MaKKRO trial

Ejemplares similares