Spatial regulation of contractility by Neuralized and Bearded during furrow invagination in Drosophila

In the Drosophila embryo, increased cortical contractility in ventral cells causes furrow formation and gastrulation. Here, the authors show that contractility is regulated by Neuralized (an E3 ubiquitin ligase) in ventral cells, and that inhibiting this process with Bearded in the ectoderm causes f...

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Autores principales:	Gantas Perez-Mockus, Khalil Mazouni, Vanessa Roca, Giulia Corradi, Vito Conte, François Schweisguth
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/24d2c0ca2e764313a9b352417c36d5de
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spelling	oai:doaj.org-article:24d2c0ca2e764313a9b352417c36d5de2021-12-02T17:06:07ZSpatial regulation of contractility by Neuralized and Bearded during furrow invagination in Drosophila10.1038/s41467-017-01482-82041-1723https://doaj.org/article/24d2c0ca2e764313a9b352417c36d5de2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01482-8https://doaj.org/toc/2041-1723In the Drosophila embryo, increased cortical contractility in ventral cells causes furrow formation and gastrulation. Here, the authors show that contractility is regulated by Neuralized (an E3 ubiquitin ligase) in ventral cells, and that inhibiting this process with Bearded in the ectoderm causes furrow invagination.Gantas Perez-MockusKhalil MazouniVanessa RocaGiulia CorradiVito ConteFrançois SchweisguthNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Gantas Perez-Mockus Khalil Mazouni Vanessa Roca Giulia Corradi Vito Conte François Schweisguth Spatial regulation of contractility by Neuralized and Bearded during furrow invagination in Drosophila
description	In the Drosophila embryo, increased cortical contractility in ventral cells causes furrow formation and gastrulation. Here, the authors show that contractility is regulated by Neuralized (an E3 ubiquitin ligase) in ventral cells, and that inhibiting this process with Bearded in the ectoderm causes furrow invagination.
format	article
author	Gantas Perez-Mockus Khalil Mazouni Vanessa Roca Giulia Corradi Vito Conte François Schweisguth
author_facet	Gantas Perez-Mockus Khalil Mazouni Vanessa Roca Giulia Corradi Vito Conte François Schweisguth
author_sort	Gantas Perez-Mockus
title	Spatial regulation of contractility by Neuralized and Bearded during furrow invagination in Drosophila
title_short	Spatial regulation of contractility by Neuralized and Bearded during furrow invagination in Drosophila
title_full	Spatial regulation of contractility by Neuralized and Bearded during furrow invagination in Drosophila
title_fullStr	Spatial regulation of contractility by Neuralized and Bearded during furrow invagination in Drosophila
title_full_unstemmed	Spatial regulation of contractility by Neuralized and Bearded during furrow invagination in Drosophila
title_sort	spatial regulation of contractility by neuralized and bearded during furrow invagination in drosophila
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/24d2c0ca2e764313a9b352417c36d5de
work_keys_str_mv	AT gantasperezmockus spatialregulationofcontractilitybyneuralizedandbeardedduringfurrowinvaginationindrosophila AT khalilmazouni spatialregulationofcontractilitybyneuralizedandbeardedduringfurrowinvaginationindrosophila AT vanessaroca spatialregulationofcontractilitybyneuralizedandbeardedduringfurrowinvaginationindrosophila AT giuliacorradi spatialregulationofcontractilitybyneuralizedandbeardedduringfurrowinvaginationindrosophila AT vitoconte spatialregulationofcontractilitybyneuralizedandbeardedduringfurrowinvaginationindrosophila AT francoisschweisguth spatialregulationofcontractilitybyneuralizedandbeardedduringfurrowinvaginationindrosophila
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Spatial regulation of contractility by Neuralized and Bearded during furrow invagination in Drosophila

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