miR-146a modulates TLR1/2 and 4 induced inflammation and links it with proliferation and lipid production via the indirect regulation of GNG7 in human SZ95 sebocytes

Abstract Activation of Toll-like receptors (TLR) 1/2 and 4 are central in inducing inflammation in sebocytes by regulating the expression of protein coding mRNAs, however the microRNA (miRNA) profile in response to TLR activation and thus the possible role of miRNAs in modulating sebocyte functions...

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Autores principales: Katalin Dull, Fruzsina Fazekas, Dávid Deák, Dóra Kovács, Szilárd Póliska, Andrea Szegedi, Christos C. Zouboulis, Dániel Törőcsik
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/24d3d019ee154af4a9038e1941abd4dc
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