A Staphylococcus pro-apoptotic peptide induces acute exacerbation of pulmonary fibrosis
Idiopathic pulmonary fibrosis is associated with increased abundance of Staphylococcus and Streptococcus in the lungs. Here, the authors identify a Staphylococcus nepalensis-derived peptide, named corisin, to induce apoptosis of lung epithelial cells and exacerbation of pulmonary fibrosis in mice.
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Nature Portfolio
2020
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oai:doaj.org-article:24d6379d02ba4aa196a47557ce97486e2021-12-02T15:39:19ZA Staphylococcus pro-apoptotic peptide induces acute exacerbation of pulmonary fibrosis10.1038/s41467-020-15344-32041-1723https://doaj.org/article/24d6379d02ba4aa196a47557ce97486e2020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15344-3https://doaj.org/toc/2041-1723Idiopathic pulmonary fibrosis is associated with increased abundance of Staphylococcus and Streptococcus in the lungs. Here, the authors identify a Staphylococcus nepalensis-derived peptide, named corisin, to induce apoptosis of lung epithelial cells and exacerbation of pulmonary fibrosis in mice.Corina N. D’Alessandro-GabazzaTetsu KobayashiTaro YasumaMasaaki TodaHeejin KimHajime FujimotoOsamu HatajiAtsuro TakeshitaKota NishihamaTomohito OkanoYuko OkanoYoichi NishiiAtsushi TomaruKentaro FujiwaraValeria Fridman D’AlessandroAhmed M. Abdel-HamidYudong RenGabriel V. PereiraChristy L. WrightAlvaro HernandezChristopher J. FieldsPeter M. YauShujie WangAkira MizoguchiMasayuki FukumuraJunpei OhtsukaTetsuya NosakaKensuke KataokaYasuhiro KondohJing WuHirokazu KawagishiYutaka YanoRoderick I. MackieIsaac CannEsteban C. GabazzaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-17 (2020) |
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DOAJ |
| collection |
DOAJ |
| language |
EN |
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Science Q |
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Science Q Corina N. D’Alessandro-Gabazza Tetsu Kobayashi Taro Yasuma Masaaki Toda Heejin Kim Hajime Fujimoto Osamu Hataji Atsuro Takeshita Kota Nishihama Tomohito Okano Yuko Okano Yoichi Nishii Atsushi Tomaru Kentaro Fujiwara Valeria Fridman D’Alessandro Ahmed M. Abdel-Hamid Yudong Ren Gabriel V. Pereira Christy L. Wright Alvaro Hernandez Christopher J. Fields Peter M. Yau Shujie Wang Akira Mizoguchi Masayuki Fukumura Junpei Ohtsuka Tetsuya Nosaka Kensuke Kataoka Yasuhiro Kondoh Jing Wu Hirokazu Kawagishi Yutaka Yano Roderick I. Mackie Isaac Cann Esteban C. Gabazza A Staphylococcus pro-apoptotic peptide induces acute exacerbation of pulmonary fibrosis |
| description |
Idiopathic pulmonary fibrosis is associated with increased abundance of Staphylococcus and Streptococcus in the lungs. Here, the authors identify a Staphylococcus nepalensis-derived peptide, named corisin, to induce apoptosis of lung epithelial cells and exacerbation of pulmonary fibrosis in mice. |
| format |
article |
| author |
Corina N. D’Alessandro-Gabazza Tetsu Kobayashi Taro Yasuma Masaaki Toda Heejin Kim Hajime Fujimoto Osamu Hataji Atsuro Takeshita Kota Nishihama Tomohito Okano Yuko Okano Yoichi Nishii Atsushi Tomaru Kentaro Fujiwara Valeria Fridman D’Alessandro Ahmed M. Abdel-Hamid Yudong Ren Gabriel V. Pereira Christy L. Wright Alvaro Hernandez Christopher J. Fields Peter M. Yau Shujie Wang Akira Mizoguchi Masayuki Fukumura Junpei Ohtsuka Tetsuya Nosaka Kensuke Kataoka Yasuhiro Kondoh Jing Wu Hirokazu Kawagishi Yutaka Yano Roderick I. Mackie Isaac Cann Esteban C. Gabazza |
| author_facet |
Corina N. D’Alessandro-Gabazza Tetsu Kobayashi Taro Yasuma Masaaki Toda Heejin Kim Hajime Fujimoto Osamu Hataji Atsuro Takeshita Kota Nishihama Tomohito Okano Yuko Okano Yoichi Nishii Atsushi Tomaru Kentaro Fujiwara Valeria Fridman D’Alessandro Ahmed M. Abdel-Hamid Yudong Ren Gabriel V. Pereira Christy L. Wright Alvaro Hernandez Christopher J. Fields Peter M. Yau Shujie Wang Akira Mizoguchi Masayuki Fukumura Junpei Ohtsuka Tetsuya Nosaka Kensuke Kataoka Yasuhiro Kondoh Jing Wu Hirokazu Kawagishi Yutaka Yano Roderick I. Mackie Isaac Cann Esteban C. Gabazza |
| author_sort |
Corina N. D’Alessandro-Gabazza |
| title |
A Staphylococcus pro-apoptotic peptide induces acute exacerbation of pulmonary fibrosis |
| title_short |
A Staphylococcus pro-apoptotic peptide induces acute exacerbation of pulmonary fibrosis |
| title_full |
A Staphylococcus pro-apoptotic peptide induces acute exacerbation of pulmonary fibrosis |
| title_fullStr |
A Staphylococcus pro-apoptotic peptide induces acute exacerbation of pulmonary fibrosis |
| title_full_unstemmed |
A Staphylococcus pro-apoptotic peptide induces acute exacerbation of pulmonary fibrosis |
| title_sort |
staphylococcus pro-apoptotic peptide induces acute exacerbation of pulmonary fibrosis |
| publisher |
Nature Portfolio |
| publishDate |
2020 |
| url |
https://doaj.org/article/24d6379d02ba4aa196a47557ce97486e |
| work_keys_str_mv |
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