Tissue Engineering Strategies for Peripheral Nerve Regeneration

A peripheral nerve injury (PNI) has severe and profound effects on the life of a patient. The therapeutic approach remains one of the most challenging clinical problems. In recent years, many constructive nerve regeneration schemes are proposed at home and abroad. Nerve tissue engineering plays an i...

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Autores principales:	Yin Li, Zhenjiang Ma, Ya Ren, Dezhi Lu, Tao Li, Wentao Li, Jinwu Wang, Hui Ma, Jie Zhao
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	peripheral nerve regeneration nerve tissue engineering pathophysiology scaffolds cells 3D printing Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/24da0f0022bf40a5968aa8b017869b43
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id	oai:doaj.org-article:24da0f0022bf40a5968aa8b017869b43
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spelling	oai:doaj.org-article:24da0f0022bf40a5968aa8b017869b432021-11-16T06:31:11ZTissue Engineering Strategies for Peripheral Nerve Regeneration1664-229510.3389/fneur.2021.768267https://doaj.org/article/24da0f0022bf40a5968aa8b017869b432021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fneur.2021.768267/fullhttps://doaj.org/toc/1664-2295A peripheral nerve injury (PNI) has severe and profound effects on the life of a patient. The therapeutic approach remains one of the most challenging clinical problems. In recent years, many constructive nerve regeneration schemes are proposed at home and abroad. Nerve tissue engineering plays an important role. It develops an ideal nerve substitute called artificial nerve. Given the complexity of nerve regeneration, this review summarizes the pathophysiology and tissue-engineered repairing strategies of the PNI. Moreover, we discussed the scaffolds and seed cells for neural tissue engineering. Furthermore, we have emphasized the role of 3D printing in tissue engineering.Yin LiZhenjiang MaYa RenDezhi LuTao LiWentao LiJinwu WangHui MaJie ZhaoFrontiers Media S.A.articleperipheral nerve regenerationnerve tissue engineeringpathophysiologyscaffoldscells3D printingNeurology. Diseases of the nervous systemRC346-429ENFrontiers in Neurology, Vol 12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	peripheral nerve regeneration nerve tissue engineering pathophysiology scaffolds cells 3D printing Neurology. Diseases of the nervous system RC346-429
spellingShingle	peripheral nerve regeneration nerve tissue engineering pathophysiology scaffolds cells 3D printing Neurology. Diseases of the nervous system RC346-429 Yin Li Zhenjiang Ma Ya Ren Dezhi Lu Tao Li Wentao Li Jinwu Wang Hui Ma Jie Zhao Tissue Engineering Strategies for Peripheral Nerve Regeneration
description	A peripheral nerve injury (PNI) has severe and profound effects on the life of a patient. The therapeutic approach remains one of the most challenging clinical problems. In recent years, many constructive nerve regeneration schemes are proposed at home and abroad. Nerve tissue engineering plays an important role. It develops an ideal nerve substitute called artificial nerve. Given the complexity of nerve regeneration, this review summarizes the pathophysiology and tissue-engineered repairing strategies of the PNI. Moreover, we discussed the scaffolds and seed cells for neural tissue engineering. Furthermore, we have emphasized the role of 3D printing in tissue engineering.
format	article
author	Yin Li Zhenjiang Ma Ya Ren Dezhi Lu Tao Li Wentao Li Jinwu Wang Hui Ma Jie Zhao
author_facet	Yin Li Zhenjiang Ma Ya Ren Dezhi Lu Tao Li Wentao Li Jinwu Wang Hui Ma Jie Zhao
author_sort	Yin Li
title	Tissue Engineering Strategies for Peripheral Nerve Regeneration
title_short	Tissue Engineering Strategies for Peripheral Nerve Regeneration
title_full	Tissue Engineering Strategies for Peripheral Nerve Regeneration
title_fullStr	Tissue Engineering Strategies for Peripheral Nerve Regeneration
title_full_unstemmed	Tissue Engineering Strategies for Peripheral Nerve Regeneration
title_sort	tissue engineering strategies for peripheral nerve regeneration
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/24da0f0022bf40a5968aa8b017869b43
work_keys_str_mv	AT yinli tissueengineeringstrategiesforperipheralnerveregeneration AT zhenjiangma tissueengineeringstrategiesforperipheralnerveregeneration AT yaren tissueengineeringstrategiesforperipheralnerveregeneration AT dezhilu tissueengineeringstrategiesforperipheralnerveregeneration AT taoli tissueengineeringstrategiesforperipheralnerveregeneration AT wentaoli tissueengineeringstrategiesforperipheralnerveregeneration AT jinwuwang tissueengineeringstrategiesforperipheralnerveregeneration AT huima tissueengineeringstrategiesforperipheralnerveregeneration AT jiezhao tissueengineeringstrategiesforperipheralnerveregeneration
_version_	1718426655733579776

Tissue Engineering Strategies for Peripheral Nerve Regeneration

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