DNA-damage foci to detect and characterize DNA repair alterations in children treated for pediatric malignancies.

<h4>Purpose</h4>In children diagnosed with cancer, we evaluated the DNA damage foci approach to identify patients with double-strand break (DSB) repair deficiencies, who may overreact to DNA-damaging radio- and chemotherapy. In one patient with Fanconi anemia (FA) suffering relapsing squ...

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Autores principales: Nadine Schuler, Jan Palm, Mareike Kaiser, Dominik Betten, Rhoikos Furtwängler, Christian Rübe, Norbert Graf, Claudia E Rübe
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/24e07093b7ed4f668b0ce7c70d15c87d
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