Processing of <italic toggle="yes">Candida albicans</italic> Ece1p Is Critical for Candidalysin Maturation and Fungal Virulence

Processing of <italic toggle="yes">Candida albicans</italic> Ece1p Is Critical for Candidalysin Maturation and Fungal Virulence

ABSTRACT Candida albicans is an opportunistic fungal pathogen responsible for superficial and life-threatening infections in humans. During mucosal infection, C. albicans undergoes a morphological transition from yeast to invasive filamentous hyphae that secrete candidalysin, a 31-amino-acid peptide...

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Main Authors: Jonathan P. Richardson, Selene Mogavero, David L. Moyes, Mariana Blagojevic, Thomas Krüger, Akash H. Verma, Bianca M. Coleman, Jacinto De La Cruz Diaz, Daniela Schulz, Nicole O. Ponde, Giulia Carrano, Olaf Kniemeyer, Duncan Wilson, Oliver Bader, Simona I. Enoiu, Jemima Ho, Nessim Kichik, Sarah L. Gaffen, Bernhard Hube, Julian R. Naglik
Format: article
Language:EN
Published: American Society for Microbiology 2018
Subjects:
Candida albicans
candidalysin
fungal infection
kexin
mucosal immunity
Microbiology
QR1-502
Online Access:https://doaj.org/article/24e176a633bf41b5807b57f22b8e6701
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