A double helical motif in OCIAD2 is essential for its localization, interactions and STAT3 activation
Abstract The Ovarian Carcinoma Immunoreactive Antigen domain (OCIAD) - containing proteins OCIAD1/Asrij and OCIAD2, are implicated in several cancers and neurodegenerative diseases. While Asrij has a conserved role in facilitating STAT3 activation for JAK/STAT signaling, the expression and function...
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Autores principales: | Saloni Sinha, Venkata Anudeep Bheemsetty, Maneesha S. Inamdar |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/24e347694055473281a5c0745a1a2906 |
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