Stress-dependent miR-980 regulation of Rbfox1/A2bp1 promotes ribonucleoprotein granule formation and cell survival
Rbfox1, a pro-survival RNA-binding protein, is expressed in a complex manner and mediates diverse developmental processes. Here, the authors observe alternative splicing of Rbfox1 and stress-dependent regulation by miR-980 in Drosophila ovaries and Rbfox1 localisation in ribonucleoprotein granules i...
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2018
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oai:doaj.org-article:24e86935154b49568d76d0c401e7ab0f2021-12-02T15:33:38ZStress-dependent miR-980 regulation of Rbfox1/A2bp1 promotes ribonucleoprotein granule formation and cell survival10.1038/s41467-017-02757-w2041-1723https://doaj.org/article/24e86935154b49568d76d0c401e7ab0f2018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02757-whttps://doaj.org/toc/2041-1723Rbfox1, a pro-survival RNA-binding protein, is expressed in a complex manner and mediates diverse developmental processes. Here, the authors observe alternative splicing of Rbfox1 and stress-dependent regulation by miR-980 in Drosophila ovaries and Rbfox1 localisation in ribonucleoprotein granules in human cells.Mariya M. KucherenkoHalyna R. ShcherbataNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-20 (2018) |
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Science Q Mariya M. Kucherenko Halyna R. Shcherbata Stress-dependent miR-980 regulation of Rbfox1/A2bp1 promotes ribonucleoprotein granule formation and cell survival |
description |
Rbfox1, a pro-survival RNA-binding protein, is expressed in a complex manner and mediates diverse developmental processes. Here, the authors observe alternative splicing of Rbfox1 and stress-dependent regulation by miR-980 in Drosophila ovaries and Rbfox1 localisation in ribonucleoprotein granules in human cells. |
format |
article |
author |
Mariya M. Kucherenko Halyna R. Shcherbata |
author_facet |
Mariya M. Kucherenko Halyna R. Shcherbata |
author_sort |
Mariya M. Kucherenko |
title |
Stress-dependent miR-980 regulation of Rbfox1/A2bp1 promotes ribonucleoprotein granule formation and cell survival |
title_short |
Stress-dependent miR-980 regulation of Rbfox1/A2bp1 promotes ribonucleoprotein granule formation and cell survival |
title_full |
Stress-dependent miR-980 regulation of Rbfox1/A2bp1 promotes ribonucleoprotein granule formation and cell survival |
title_fullStr |
Stress-dependent miR-980 regulation of Rbfox1/A2bp1 promotes ribonucleoprotein granule formation and cell survival |
title_full_unstemmed |
Stress-dependent miR-980 regulation of Rbfox1/A2bp1 promotes ribonucleoprotein granule formation and cell survival |
title_sort |
stress-dependent mir-980 regulation of rbfox1/a2bp1 promotes ribonucleoprotein granule formation and cell survival |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/24e86935154b49568d76d0c401e7ab0f |
work_keys_str_mv |
AT mariyamkucherenko stressdependentmir980regulationofrbfox1a2bp1promotesribonucleoproteingranuleformationandcellsurvival AT halynarshcherbata stressdependentmir980regulationofrbfox1a2bp1promotesribonucleoproteingranuleformationandcellsurvival |
_version_ |
1718387070716608512 |