In vivo enrichment of busulfan-resistant germ cells for efficient production of transgenic avian models

Abstract Most transgenic animals are generated using a genome-modified stem cell system and genome modification directly in embryos. Although this system is well-established in the development of transgenic animals, donor cell-derived transgenic animal production is inefficient in some cases. Especi...

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Autores principales: Young Min Kim, Kyung Je Park, Jin Se Park, Kyung Min Jung, Jae Yong Han
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/24fcf1f8897443d8a5fd8682c357cdfb
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