Thiosemicarbazone Copper Chelator BLT-1 Blocks Apicomplexan Parasite Replication by Selective Inhibition of Scavenger Receptor B Type 1 (SR-BI)

Coccidian parasites are obligate intracellular pathogens that affect humans and animals. Apicomplexans are defective in de novo synthesis of cholesterol, which is required for membrane biosynthesis and offspring formation. In consequence, cholesterol has to be scavenged from host cells. It is mainly...

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Bibliographic Details
Main Authors: Camilo Larrazabal, Sara López-Osorio, Zahady D. Velásquez, Carlos Hermosilla, Anja Taubert, Liliana M. R. Silva
Format: article
Language:EN
Published: MDPI AG 2021
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Online Access:https://doaj.org/article/24fecbc6af05416292a514b764d8e898
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