Function and molecular mechanism of N-terminal acetylation in autophagy

Summary: Acetyl ligation to the amino acids in a protein is an important posttranslational modification. However, in contrast to lysine acetylation, N-terminal acetylation is elusive in terms of its cellular functions. Here, we identify Nat3 as an N-terminal acetyltransferase essential for autophagy...

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Autores principales: Tianyun Shen, Lan Jiang, Xinyuan Wang, Qingjia Xu, Lu Han, Shiyan Liu, Ting Huang, Hongyan Li, Lunzhi Dai, Huihui Li, Kefeng Lu
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/24ffbeca3fe74fd693bbb1b3f4b3f6ca
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