Live imaging of alveologenesis in precision-cut lung slices reveals dynamic epithelial cell behaviour

The process of alveologenesis is incompletely understood, partly due to the lack of applicable real-time imaging methods. Here the authors describe the process of alveologenesis and the behaviour of epithelial cells in real-time, using widefield microscopy and image deconvolution in precision-cut lu...

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Autores principales:	Khondoker M. Akram, Laura L. Yates, Róisín Mongey, Stephen Rothery, David C. A. Gaboriau, Jeremy Sanderson, Matthew Hind, Mark Griffiths, Charlotte H. Dean
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/24ffe26043ce43fea34a19872584d905
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id	oai:doaj.org-article:24ffe26043ce43fea34a19872584d905
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spelling	oai:doaj.org-article:24ffe26043ce43fea34a19872584d9052021-12-02T16:57:07ZLive imaging of alveologenesis in precision-cut lung slices reveals dynamic epithelial cell behaviour10.1038/s41467-019-09067-32041-1723https://doaj.org/article/24ffe26043ce43fea34a19872584d9052019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09067-3https://doaj.org/toc/2041-1723The process of alveologenesis is incompletely understood, partly due to the lack of applicable real-time imaging methods. Here the authors describe the process of alveologenesis and the behaviour of epithelial cells in real-time, using widefield microscopy and image deconvolution in precision-cut lung slices, revealing the dominant role of epithelial cell migration.Khondoker M. AkramLaura L. YatesRóisín MongeyStephen RotheryDavid C. A. GaboriauJeremy SandersonMatthew HindMark GriffithsCharlotte H. DeanNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Khondoker M. Akram Laura L. Yates Róisín Mongey Stephen Rothery David C. A. Gaboriau Jeremy Sanderson Matthew Hind Mark Griffiths Charlotte H. Dean Live imaging of alveologenesis in precision-cut lung slices reveals dynamic epithelial cell behaviour
description	The process of alveologenesis is incompletely understood, partly due to the lack of applicable real-time imaging methods. Here the authors describe the process of alveologenesis and the behaviour of epithelial cells in real-time, using widefield microscopy and image deconvolution in precision-cut lung slices, revealing the dominant role of epithelial cell migration.
format	article
author	Khondoker M. Akram Laura L. Yates Róisín Mongey Stephen Rothery David C. A. Gaboriau Jeremy Sanderson Matthew Hind Mark Griffiths Charlotte H. Dean
author_facet	Khondoker M. Akram Laura L. Yates Róisín Mongey Stephen Rothery David C. A. Gaboriau Jeremy Sanderson Matthew Hind Mark Griffiths Charlotte H. Dean
author_sort	Khondoker M. Akram
title	Live imaging of alveologenesis in precision-cut lung slices reveals dynamic epithelial cell behaviour
title_short	Live imaging of alveologenesis in precision-cut lung slices reveals dynamic epithelial cell behaviour
title_full	Live imaging of alveologenesis in precision-cut lung slices reveals dynamic epithelial cell behaviour
title_fullStr	Live imaging of alveologenesis in precision-cut lung slices reveals dynamic epithelial cell behaviour
title_full_unstemmed	Live imaging of alveologenesis in precision-cut lung slices reveals dynamic epithelial cell behaviour
title_sort	live imaging of alveologenesis in precision-cut lung slices reveals dynamic epithelial cell behaviour
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/24ffe26043ce43fea34a19872584d905
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Live imaging of alveologenesis in precision-cut lung slices reveals dynamic epithelial cell behaviour

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