Ecdysone regulates Drosophila wing disc size via a TORC1 dependent mechanism

During development, organs grow to achieve a size necessary for their function; how final organ size is sensed to trigger growth arrest, however, remains unclear. Here the authors show that Drosophila wing disc size is determined by the hormone ecdysone through a TORC1-dependent mechanism.

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Detalles Bibliográficos
Autores principales: Katrin Strassburger, Marilena Lutz, Sandra Müller, Aurelio A. Teleman
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/25063e245235444b9eb98e481187274f
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Sumario:During development, organs grow to achieve a size necessary for their function; how final organ size is sensed to trigger growth arrest, however, remains unclear. Here the authors show that Drosophila wing disc size is determined by the hormone ecdysone through a TORC1-dependent mechanism.