Ecdysone regulates Drosophila wing disc size via a TORC1 dependent mechanism
During development, organs grow to achieve a size necessary for their function; how final organ size is sensed to trigger growth arrest, however, remains unclear. Here the authors show that Drosophila wing disc size is determined by the hormone ecdysone through a TORC1-dependent mechanism.
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Nature Portfolio
2021
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oai:doaj.org-article:25063e245235444b9eb98e481187274f2021-11-21T12:35:26ZEcdysone regulates Drosophila wing disc size via a TORC1 dependent mechanism10.1038/s41467-021-26780-02041-1723https://doaj.org/article/25063e245235444b9eb98e481187274f2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26780-0https://doaj.org/toc/2041-1723During development, organs grow to achieve a size necessary for their function; how final organ size is sensed to trigger growth arrest, however, remains unclear. Here the authors show that Drosophila wing disc size is determined by the hormone ecdysone through a TORC1-dependent mechanism.Katrin StrassburgerMarilena LutzSandra MüllerAurelio A. TelemanNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021) |
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Science Q Katrin Strassburger Marilena Lutz Sandra Müller Aurelio A. Teleman Ecdysone regulates Drosophila wing disc size via a TORC1 dependent mechanism |
description |
During development, organs grow to achieve a size necessary for their function; how final organ size is sensed to trigger growth arrest, however, remains unclear. Here the authors show that Drosophila wing disc size is determined by the hormone ecdysone through a TORC1-dependent mechanism. |
format |
article |
author |
Katrin Strassburger Marilena Lutz Sandra Müller Aurelio A. Teleman |
author_facet |
Katrin Strassburger Marilena Lutz Sandra Müller Aurelio A. Teleman |
author_sort |
Katrin Strassburger |
title |
Ecdysone regulates Drosophila wing disc size via a TORC1 dependent mechanism |
title_short |
Ecdysone regulates Drosophila wing disc size via a TORC1 dependent mechanism |
title_full |
Ecdysone regulates Drosophila wing disc size via a TORC1 dependent mechanism |
title_fullStr |
Ecdysone regulates Drosophila wing disc size via a TORC1 dependent mechanism |
title_full_unstemmed |
Ecdysone regulates Drosophila wing disc size via a TORC1 dependent mechanism |
title_sort |
ecdysone regulates drosophila wing disc size via a torc1 dependent mechanism |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/25063e245235444b9eb98e481187274f |
work_keys_str_mv |
AT katrinstrassburger ecdysoneregulatesdrosophilawingdiscsizeviaatorc1dependentmechanism AT marilenalutz ecdysoneregulatesdrosophilawingdiscsizeviaatorc1dependentmechanism AT sandramuller ecdysoneregulatesdrosophilawingdiscsizeviaatorc1dependentmechanism AT aurelioateleman ecdysoneregulatesdrosophilawingdiscsizeviaatorc1dependentmechanism |
_version_ |
1718418873663881216 |