Ecdysone regulates Drosophila wing disc size via a TORC1 dependent mechanism

During development, organs grow to achieve a size necessary for their function; how final organ size is sensed to trigger growth arrest, however, remains unclear. Here the authors show that Drosophila wing disc size is determined by the hormone ecdysone through a TORC1-dependent mechanism.

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Autores principales: Katrin Strassburger, Marilena Lutz, Sandra Müller, Aurelio A. Teleman
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/25063e245235444b9eb98e481187274f
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spelling oai:doaj.org-article:25063e245235444b9eb98e481187274f2021-11-21T12:35:26ZEcdysone regulates Drosophila wing disc size via a TORC1 dependent mechanism10.1038/s41467-021-26780-02041-1723https://doaj.org/article/25063e245235444b9eb98e481187274f2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26780-0https://doaj.org/toc/2041-1723During development, organs grow to achieve a size necessary for their function; how final organ size is sensed to trigger growth arrest, however, remains unclear. Here the authors show that Drosophila wing disc size is determined by the hormone ecdysone through a TORC1-dependent mechanism.Katrin StrassburgerMarilena LutzSandra MüllerAurelio A. TelemanNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Katrin Strassburger
Marilena Lutz
Sandra Müller
Aurelio A. Teleman
Ecdysone regulates Drosophila wing disc size via a TORC1 dependent mechanism
description During development, organs grow to achieve a size necessary for their function; how final organ size is sensed to trigger growth arrest, however, remains unclear. Here the authors show that Drosophila wing disc size is determined by the hormone ecdysone through a TORC1-dependent mechanism.
format article
author Katrin Strassburger
Marilena Lutz
Sandra Müller
Aurelio A. Teleman
author_facet Katrin Strassburger
Marilena Lutz
Sandra Müller
Aurelio A. Teleman
author_sort Katrin Strassburger
title Ecdysone regulates Drosophila wing disc size via a TORC1 dependent mechanism
title_short Ecdysone regulates Drosophila wing disc size via a TORC1 dependent mechanism
title_full Ecdysone regulates Drosophila wing disc size via a TORC1 dependent mechanism
title_fullStr Ecdysone regulates Drosophila wing disc size via a TORC1 dependent mechanism
title_full_unstemmed Ecdysone regulates Drosophila wing disc size via a TORC1 dependent mechanism
title_sort ecdysone regulates drosophila wing disc size via a torc1 dependent mechanism
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/25063e245235444b9eb98e481187274f
work_keys_str_mv AT katrinstrassburger ecdysoneregulatesdrosophilawingdiscsizeviaatorc1dependentmechanism
AT marilenalutz ecdysoneregulatesdrosophilawingdiscsizeviaatorc1dependentmechanism
AT sandramuller ecdysoneregulatesdrosophilawingdiscsizeviaatorc1dependentmechanism
AT aurelioateleman ecdysoneregulatesdrosophilawingdiscsizeviaatorc1dependentmechanism
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