Brain Tumor Heterogeneity

Tumor heterogeneity is the concept that different tumor cells provide distinct biomorphological lesions, gene expressions, proliferation, microenvironment and graduated capacity of metastatic lesions. Brain tumor heterogeneity has been recently discussed about the interesting interaction of chronic...

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Autores principales:	Telmo Augusto Barba Belsuzarri, Maick Willen Fernandes Neves, Otávio Augusto da Costa, Diego Alves Soares, Fernando Antônio de Melo Filho, Mariana Mazzuia Guimarães, Tiago Fernandes Gonçales, Wolnei Marques Zeviani, João Flávio Mattos Araújo
Formato:	article
Lenguaje:	EN
Publicado:	Thieme Revinter Publicações Ltda. 2018
Materias:	brain tumor tumor heterogeneity glioma stem cell genetics epigenetics microenvironment Medicine R Surgery RD1-811
Acceso en línea:	https://doaj.org/article/2507634095fa4af69ede651b774f7c1e
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:2507634095fa4af69ede651b774f7c1e2021-11-03T23:45:46ZBrain Tumor Heterogeneity0103-53552359-592210.1055/s-0038-1625962https://doaj.org/article/2507634095fa4af69ede651b774f7c1e2018-03-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1625962https://doaj.org/toc/0103-5355https://doaj.org/toc/2359-5922Tumor heterogeneity is the concept that different tumor cells provide distinct biomorphological lesions, gene expressions, proliferation, microenvironment and graduated capacity of metastatic lesions. Brain tumor heterogeneity has been recently discussed about the interesting interaction of chronic inflammation, microenvironment, epigenetics and glioma steam cells. Brain tumors remain a challenge with regards to medication and disease, due to the lack of treatment options and unsatisfactory results. These results might be the result of the brain tumor heterogeneity and its multiple resistance mechanisms to chemo and radiotherapy.Telmo Augusto Barba BelsuzarriMaick Willen Fernandes NevesOtávio Augusto da CostaDiego Alves SoaresFernando Antônio de Melo FilhoMariana Mazzuia GuimarãesTiago Fernandes GonçalesWolnei Marques ZevianiJoão Flávio Mattos AraújoThieme Revinter Publicações Ltda.articlebrain tumortumor heterogeneityglioma stem cellgeneticsepigeneticsmicroenvironmentMedicineRSurgeryRD1-811ENBrazilian Neurosurgery, Vol 40, Iss 03, Pp e253-e256 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	brain tumor tumor heterogeneity glioma stem cell genetics epigenetics microenvironment Medicine R Surgery RD1-811
spellingShingle	brain tumor tumor heterogeneity glioma stem cell genetics epigenetics microenvironment Medicine R Surgery RD1-811 Telmo Augusto Barba Belsuzarri Maick Willen Fernandes Neves Otávio Augusto da Costa Diego Alves Soares Fernando Antônio de Melo Filho Mariana Mazzuia Guimarães Tiago Fernandes Gonçales Wolnei Marques Zeviani João Flávio Mattos Araújo Brain Tumor Heterogeneity
description	Tumor heterogeneity is the concept that different tumor cells provide distinct biomorphological lesions, gene expressions, proliferation, microenvironment and graduated capacity of metastatic lesions. Brain tumor heterogeneity has been recently discussed about the interesting interaction of chronic inflammation, microenvironment, epigenetics and glioma steam cells. Brain tumors remain a challenge with regards to medication and disease, due to the lack of treatment options and unsatisfactory results. These results might be the result of the brain tumor heterogeneity and its multiple resistance mechanisms to chemo and radiotherapy.
format	article
author	Telmo Augusto Barba Belsuzarri Maick Willen Fernandes Neves Otávio Augusto da Costa Diego Alves Soares Fernando Antônio de Melo Filho Mariana Mazzuia Guimarães Tiago Fernandes Gonçales Wolnei Marques Zeviani João Flávio Mattos Araújo
author_facet	Telmo Augusto Barba Belsuzarri Maick Willen Fernandes Neves Otávio Augusto da Costa Diego Alves Soares Fernando Antônio de Melo Filho Mariana Mazzuia Guimarães Tiago Fernandes Gonçales Wolnei Marques Zeviani João Flávio Mattos Araújo
author_sort	Telmo Augusto Barba Belsuzarri
title	Brain Tumor Heterogeneity
title_short	Brain Tumor Heterogeneity
title_full	Brain Tumor Heterogeneity
title_fullStr	Brain Tumor Heterogeneity
title_full_unstemmed	Brain Tumor Heterogeneity
title_sort	brain tumor heterogeneity
publisher	Thieme Revinter Publicações Ltda.
publishDate	2018
url	https://doaj.org/article/2507634095fa4af69ede651b774f7c1e
work_keys_str_mv	AT telmoaugustobarbabelsuzarri braintumorheterogeneity AT maickwillenfernandesneves braintumorheterogeneity AT otavioaugustodacosta braintumorheterogeneity AT diegoalvessoares braintumorheterogeneity AT fernandoantoniodemelofilho braintumorheterogeneity AT marianamazzuiaguimaraes braintumorheterogeneity AT tiagofernandesgoncales braintumorheterogeneity AT wolneimarqueszeviani braintumorheterogeneity AT joaoflaviomattosaraujo braintumorheterogeneity
_version_	1718445319151157248

Brain Tumor Heterogeneity

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