PTEN suppresses epithelial–mesenchymal transition and cancer stem cell activity by downregulating Abi1

PTEN suppresses epithelial–mesenchymal transition and cancer stem cell activity by downregulating Abi1

Abstract The epithelial–mesenchymal transition (EMT) is an embryonic program frequently reactivated during cancer progression and is implicated in cancer invasion and metastasis. Cancer cells can also acquire stem cell properties to self-renew and give rise to new tumors through the EMT. Inactivatio...

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Autores principales: Yanmei Qi, Jie Liu, Joshua Chao, Mark P. Scheuerman, Saum A. Rahimi, Leonard Y. Lee, Shaohua Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Medicine
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Science
Q
Acceso en línea:https://doaj.org/article/250e7653b49d4b5ab298c891dfc9a266
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