Graham-Little-Piccardi-Lassueur Syndrome: Two Case Reports and Review of the Literature

Graham-Little-Piccardi-Lassueur syndrome (GLPLS) is a rare syndrome characterized by the triad of cicatricial alopecia of the scalp, non-cicatricial alopecia of the axilla and groin and follicular lichen planus eruptions on the trunk and extremities. GLPLS is considered to be a variant of lichen pla...

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Autores principales:	Dourmishev L., Mironova N., Popov I., Rusinova D., Balabanova M., Miteva L.
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2020
Materias:	lichen planopilaris cicatricial alopecia graham-little-piccardi-lassueur syndrome Medicine R
Acceso en línea:	https://doaj.org/article/251079f65f894488830fc69ca07c1d2d
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spelling	oai:doaj.org-article:251079f65f894488830fc69ca07c1d2d2021-12-02T18:16:00ZGraham-Little-Piccardi-Lassueur Syndrome: Two Case Reports and Review of the Literature0324-175010.2478/amb-2020-0047https://doaj.org/article/251079f65f894488830fc69ca07c1d2d2020-11-01T00:00:00Zhttps://doi.org/10.2478/amb-2020-0047https://doaj.org/toc/0324-1750Graham-Little-Piccardi-Lassueur syndrome (GLPLS) is a rare syndrome characterized by the triad of cicatricial alopecia of the scalp, non-cicatricial alopecia of the axilla and groin and follicular lichen planus eruptions on the trunk and extremities. GLPLS is considered to be a variant of lichen planopilaris. We report two cases that have fulfilled all of the criteria for GLPLS. The first case was a 71-year-old woman, admitted to the Department of Dermatology for pruritic perifollicullar erythema and scaling of the scalp, cicatricial scalp alopecia and hair loss of the axilla and pubic region for five months. Subsequently, follicular hyperkeratotic eruptions and hyperpigmented macules on the skin of the chest and abdomen appeared. The second case was a 48-year-old man with pruritic follicular papules on the face, trunk and extremities for four months. All of the laboratory examinations in both patients were within normal limits. No alternation in the general condition of the patients was observed. Histological examinations in both patients confirmed the diagnosis GLPLS. The patients were treated with systemic and local corticosteroid resulting in marked improvement of the skin lesions; however, cicatricial scalp alopecia showed no response to the treatment.Dourmishev L.Mironova N.Popov I.Rusinova D.Balabanova M.Miteva L.Sciendoarticlelichen planopilariscicatricial alopeciagraham-little-piccardi-lassueur syndromeMedicineRENActa Medica Bulgarica, Vol 47, Iss 4, Pp 58-62 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	lichen planopilaris cicatricial alopecia graham-little-piccardi-lassueur syndrome Medicine R
spellingShingle	lichen planopilaris cicatricial alopecia graham-little-piccardi-lassueur syndrome Medicine R Dourmishev L. Mironova N. Popov I. Rusinova D. Balabanova M. Miteva L. Graham-Little-Piccardi-Lassueur Syndrome: Two Case Reports and Review of the Literature
description	Graham-Little-Piccardi-Lassueur syndrome (GLPLS) is a rare syndrome characterized by the triad of cicatricial alopecia of the scalp, non-cicatricial alopecia of the axilla and groin and follicular lichen planus eruptions on the trunk and extremities. GLPLS is considered to be a variant of lichen planopilaris. We report two cases that have fulfilled all of the criteria for GLPLS. The first case was a 71-year-old woman, admitted to the Department of Dermatology for pruritic perifollicullar erythema and scaling of the scalp, cicatricial scalp alopecia and hair loss of the axilla and pubic region for five months. Subsequently, follicular hyperkeratotic eruptions and hyperpigmented macules on the skin of the chest and abdomen appeared. The second case was a 48-year-old man with pruritic follicular papules on the face, trunk and extremities for four months. All of the laboratory examinations in both patients were within normal limits. No alternation in the general condition of the patients was observed. Histological examinations in both patients confirmed the diagnosis GLPLS. The patients were treated with systemic and local corticosteroid resulting in marked improvement of the skin lesions; however, cicatricial scalp alopecia showed no response to the treatment.
format	article
author	Dourmishev L. Mironova N. Popov I. Rusinova D. Balabanova M. Miteva L.
author_facet	Dourmishev L. Mironova N. Popov I. Rusinova D. Balabanova M. Miteva L.
author_sort	Dourmishev L.
title	Graham-Little-Piccardi-Lassueur Syndrome: Two Case Reports and Review of the Literature
title_short	Graham-Little-Piccardi-Lassueur Syndrome: Two Case Reports and Review of the Literature
title_full	Graham-Little-Piccardi-Lassueur Syndrome: Two Case Reports and Review of the Literature
title_fullStr	Graham-Little-Piccardi-Lassueur Syndrome: Two Case Reports and Review of the Literature
title_full_unstemmed	Graham-Little-Piccardi-Lassueur Syndrome: Two Case Reports and Review of the Literature
title_sort	graham-little-piccardi-lassueur syndrome: two case reports and review of the literature
publisher	Sciendo
publishDate	2020
url	https://doaj.org/article/251079f65f894488830fc69ca07c1d2d
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Graham-Little-Piccardi-Lassueur Syndrome: Two Case Reports and Review of the Literature

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