A joint view on genetic variants for adiposity differentiates subtypes with distinct metabolic implications

A joint view on genetic variants for adiposity differentiates subtypes with distinct metabolic implications

In GWAS, waist-to-hip ratio (WHR) is often adjusted for body mass index (BMI) to account for their correlation (WHRadjBMI). Here, Winkler et al. classify 159 genetic variants for BMI, WHR, or WHRadjBMI based on their effect directions for BMI and WHR to differentiate subtypes of adiposity genetics.

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Detalles Bibliográficos
Autores principales: Thomas W Winkler, Felix Günther, Simon Höllerer, Martina Zimmermann, Ruth JF Loos, Zoltán Kutalik, Iris M Heid
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/2516e462a68a41d99eb56cc05ac33e13
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