YtfK activates the stringent response by triggering the alarmone synthetase SpoT in Escherichia coli

The enzyme SpoT is important for accumulation of the alarmone (p)ppGpp, which triggers the stringent response in E. coli. Here, Germain et al. show that the protein YtfK promotes SpoT-dependent accumulation of (p)ppGpp and is required for activation of the stringent response during phosphate and fat...

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Autores principales:	Elsa Germain, Paul Guiraud, Deborah Byrne, Badreddine Douzi, Meriem Djendli, Etienne Maisonneuve
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/251aec81b0e44efd978aba7078ab0128
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spelling	oai:doaj.org-article:251aec81b0e44efd978aba7078ab01282021-12-02T15:36:02ZYtfK activates the stringent response by triggering the alarmone synthetase SpoT in Escherichia coli10.1038/s41467-019-13764-42041-1723https://doaj.org/article/251aec81b0e44efd978aba7078ab01282019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13764-4https://doaj.org/toc/2041-1723The enzyme SpoT is important for accumulation of the alarmone (p)ppGpp, which triggers the stringent response in E. coli. Here, Germain et al. show that the protein YtfK promotes SpoT-dependent accumulation of (p)ppGpp and is required for activation of the stringent response during phosphate and fatty acid starvation.Elsa GermainPaul GuiraudDeborah ByrneBadreddine DouziMeriem DjendliEtienne MaisonneuveNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Elsa Germain Paul Guiraud Deborah Byrne Badreddine Douzi Meriem Djendli Etienne Maisonneuve YtfK activates the stringent response by triggering the alarmone synthetase SpoT in Escherichia coli
description	The enzyme SpoT is important for accumulation of the alarmone (p)ppGpp, which triggers the stringent response in E. coli. Here, Germain et al. show that the protein YtfK promotes SpoT-dependent accumulation of (p)ppGpp and is required for activation of the stringent response during phosphate and fatty acid starvation.
format	article
author	Elsa Germain Paul Guiraud Deborah Byrne Badreddine Douzi Meriem Djendli Etienne Maisonneuve
author_facet	Elsa Germain Paul Guiraud Deborah Byrne Badreddine Douzi Meriem Djendli Etienne Maisonneuve
author_sort	Elsa Germain
title	YtfK activates the stringent response by triggering the alarmone synthetase SpoT in Escherichia coli
title_short	YtfK activates the stringent response by triggering the alarmone synthetase SpoT in Escherichia coli
title_full	YtfK activates the stringent response by triggering the alarmone synthetase SpoT in Escherichia coli
title_fullStr	YtfK activates the stringent response by triggering the alarmone synthetase SpoT in Escherichia coli
title_full_unstemmed	YtfK activates the stringent response by triggering the alarmone synthetase SpoT in Escherichia coli
title_sort	ytfk activates the stringent response by triggering the alarmone synthetase spot in escherichia coli
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/251aec81b0e44efd978aba7078ab0128
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YtfK activates the stringent response by triggering the alarmone synthetase SpoT in Escherichia coli

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