Regulatory Role of microRNAs in Tumor Angiogenesis

The process of neoangiogenesis is one of the classic hallmarks of a cancer. Its intricate mechanisms have long been one of the major domains in cancer research and a hope for a therapeutic breakthrough. Last decade a new subgroup of non-coding RNA molecules was reported called microRNAs. Literally h...

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Autores principales:	Popov T., Giragosyan S., Petkova V., Marinov Tz., Belitova M., Rangachev J., Kaneva R., Mitev V.
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2020
Materias:	tumor angiogenesis microrna vegf-a hif hif switch Medicine R
Acceso en línea:	https://doaj.org/article/251feebad4f04e15b42ad73fe4d25832
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spelling	oai:doaj.org-article:251feebad4f04e15b42ad73fe4d258322021-12-02T19:11:31ZRegulatory Role of microRNAs in Tumor Angiogenesis0324-175010.2478/amb-2020-0012https://doaj.org/article/251feebad4f04e15b42ad73fe4d258322020-05-01T00:00:00Zhttps://doi.org/10.2478/amb-2020-0012https://doaj.org/toc/0324-1750The process of neoangiogenesis is one of the classic hallmarks of a cancer. Its intricate mechanisms have long been one of the major domains in cancer research and a hope for a therapeutic breakthrough. Last decade a new subgroup of non-coding RNA molecules was reported called microRNAs. Literally hundreds of new molecules in this class are being uncovered as pivotal regulators in virtually all intracellular processes. The aim of this study is to classify and review those microRNA molecules that have a role in the processes of tumor angiogenesis and map their places in the regulatory framework of the classical proangiogenic genes and their canonical cascades.Popov T.Giragosyan S.Petkova V.Marinov Tz.Belitova M.Rangachev J.Kaneva R.Mitev V.Sciendoarticletumor angiogenesismicrornavegf-ahifhif switchMedicineRENActa Medica Bulgarica, Vol 47, Iss 1, Pp 67-72 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	tumor angiogenesis microrna vegf-a hif hif switch Medicine R
spellingShingle	tumor angiogenesis microrna vegf-a hif hif switch Medicine R Popov T. Giragosyan S. Petkova V. Marinov Tz. Belitova M. Rangachev J. Kaneva R. Mitev V. Regulatory Role of microRNAs in Tumor Angiogenesis
description	The process of neoangiogenesis is one of the classic hallmarks of a cancer. Its intricate mechanisms have long been one of the major domains in cancer research and a hope for a therapeutic breakthrough. Last decade a new subgroup of non-coding RNA molecules was reported called microRNAs. Literally hundreds of new molecules in this class are being uncovered as pivotal regulators in virtually all intracellular processes. The aim of this study is to classify and review those microRNA molecules that have a role in the processes of tumor angiogenesis and map their places in the regulatory framework of the classical proangiogenic genes and their canonical cascades.
format	article
author	Popov T. Giragosyan S. Petkova V. Marinov Tz. Belitova M. Rangachev J. Kaneva R. Mitev V.
author_facet	Popov T. Giragosyan S. Petkova V. Marinov Tz. Belitova M. Rangachev J. Kaneva R. Mitev V.
author_sort	Popov T.
title	Regulatory Role of microRNAs in Tumor Angiogenesis
title_short	Regulatory Role of microRNAs in Tumor Angiogenesis
title_full	Regulatory Role of microRNAs in Tumor Angiogenesis
title_fullStr	Regulatory Role of microRNAs in Tumor Angiogenesis
title_full_unstemmed	Regulatory Role of microRNAs in Tumor Angiogenesis
title_sort	regulatory role of micrornas in tumor angiogenesis
publisher	Sciendo
publishDate	2020
url	https://doaj.org/article/251feebad4f04e15b42ad73fe4d25832
work_keys_str_mv	AT popovt regulatoryroleofmicrornasintumorangiogenesis AT giragosyans regulatoryroleofmicrornasintumorangiogenesis AT petkovav regulatoryroleofmicrornasintumorangiogenesis AT marinovtz regulatoryroleofmicrornasintumorangiogenesis AT belitovam regulatoryroleofmicrornasintumorangiogenesis AT rangachevj regulatoryroleofmicrornasintumorangiogenesis AT kanevar regulatoryroleofmicrornasintumorangiogenesis AT mitevv regulatoryroleofmicrornasintumorangiogenesis
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Regulatory Role of microRNAs in Tumor Angiogenesis

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