Risk Factors For Radiation-Induced Skin Ulceration in Percutaneous Coronary Interventions of Chronic Total Occluded Lesions: A 2-Year Observational Study

Abstract Relationship between radiation-induced skin ulceration (RSU) and variables in percutaneous coronary interventions (PCI) was rarely reported. RSU is a severe complication in PCIs, especially for chronic total occlusion (CTO) lesions. We investigated the RSUs and their risk factors in patient...

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Autores principales:	Chi-Cheng Lai, Kai-Che Wei, Wen-Yee Chen, Guang-Yuan Mar, Wen-Hwa Wang, Chieh-Shan Wu, Ching-Jiunn Tseng, Kuo-Chung Yang, Lee-Wei Chen, Chun-Peng Liu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/2522ee694d03434bbd57160c822b8aaa
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spelling	oai:doaj.org-article:2522ee694d03434bbd57160c822b8aaa2021-12-02T11:40:34ZRisk Factors For Radiation-Induced Skin Ulceration in Percutaneous Coronary Interventions of Chronic Total Occluded Lesions: A 2-Year Observational Study10.1038/s41598-017-08945-42045-2322https://doaj.org/article/2522ee694d03434bbd57160c822b8aaa2017-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-08945-4https://doaj.org/toc/2045-2322Abstract Relationship between radiation-induced skin ulceration (RSU) and variables in percutaneous coronary interventions (PCI) was rarely reported. RSU is a severe complication in PCIs, especially for chronic total occlusion (CTO) lesions. We investigated the RSUs and their risk factors in patients receiving CTO PCIs over a 2-year period. Data were analyzed using chi-square tests, t-tests and receiver operating characteristic (ROC) curve. Of 238 patients, 11 patients (4.6%) had RSUs all at right upper back. RSUs were significantly associated with use of left anterior oblique (LAO) views (100% vs. 47.1%, p < 0.001), retrograde techniques (36.3% vs. 7.9%, p = 0.012), or a procedure time (PT) defined as a time duration between the first and last angiograms of > 120, 180, or 240 minutes (p < 0.05). ROC analysis showed a long PT was an accurate predictor of RSUs (AUC = 0.88; p < 0.001) at a cut-off of 130 minutes (sensitivity = 0.91, specificity = 0.81). The results showed risk factors for RSUs containing use of large LAO views, retrograde techniques, and prolonged PTs. This study suggests that, to minimize RSU, interventionalists should limit PT to roughly 2 hours in fixed LAO views.Chi-Cheng LaiKai-Che WeiWen-Yee ChenGuang-Yuan MarWen-Hwa WangChieh-Shan WuChing-Jiunn TsengKuo-Chung YangLee-Wei ChenChun-Peng LiuNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Chi-Cheng Lai Kai-Che Wei Wen-Yee Chen Guang-Yuan Mar Wen-Hwa Wang Chieh-Shan Wu Ching-Jiunn Tseng Kuo-Chung Yang Lee-Wei Chen Chun-Peng Liu Risk Factors For Radiation-Induced Skin Ulceration in Percutaneous Coronary Interventions of Chronic Total Occluded Lesions: A 2-Year Observational Study
description	Abstract Relationship between radiation-induced skin ulceration (RSU) and variables in percutaneous coronary interventions (PCI) was rarely reported. RSU is a severe complication in PCIs, especially for chronic total occlusion (CTO) lesions. We investigated the RSUs and their risk factors in patients receiving CTO PCIs over a 2-year period. Data were analyzed using chi-square tests, t-tests and receiver operating characteristic (ROC) curve. Of 238 patients, 11 patients (4.6%) had RSUs all at right upper back. RSUs were significantly associated with use of left anterior oblique (LAO) views (100% vs. 47.1%, p < 0.001), retrograde techniques (36.3% vs. 7.9%, p = 0.012), or a procedure time (PT) defined as a time duration between the first and last angiograms of > 120, 180, or 240 minutes (p < 0.05). ROC analysis showed a long PT was an accurate predictor of RSUs (AUC = 0.88; p < 0.001) at a cut-off of 130 minutes (sensitivity = 0.91, specificity = 0.81). The results showed risk factors for RSUs containing use of large LAO views, retrograde techniques, and prolonged PTs. This study suggests that, to minimize RSU, interventionalists should limit PT to roughly 2 hours in fixed LAO views.
format	article
author	Chi-Cheng Lai Kai-Che Wei Wen-Yee Chen Guang-Yuan Mar Wen-Hwa Wang Chieh-Shan Wu Ching-Jiunn Tseng Kuo-Chung Yang Lee-Wei Chen Chun-Peng Liu
author_facet	Chi-Cheng Lai Kai-Che Wei Wen-Yee Chen Guang-Yuan Mar Wen-Hwa Wang Chieh-Shan Wu Ching-Jiunn Tseng Kuo-Chung Yang Lee-Wei Chen Chun-Peng Liu
author_sort	Chi-Cheng Lai
title	Risk Factors For Radiation-Induced Skin Ulceration in Percutaneous Coronary Interventions of Chronic Total Occluded Lesions: A 2-Year Observational Study
title_short	Risk Factors For Radiation-Induced Skin Ulceration in Percutaneous Coronary Interventions of Chronic Total Occluded Lesions: A 2-Year Observational Study
title_full	Risk Factors For Radiation-Induced Skin Ulceration in Percutaneous Coronary Interventions of Chronic Total Occluded Lesions: A 2-Year Observational Study
title_fullStr	Risk Factors For Radiation-Induced Skin Ulceration in Percutaneous Coronary Interventions of Chronic Total Occluded Lesions: A 2-Year Observational Study
title_full_unstemmed	Risk Factors For Radiation-Induced Skin Ulceration in Percutaneous Coronary Interventions of Chronic Total Occluded Lesions: A 2-Year Observational Study
title_sort	risk factors for radiation-induced skin ulceration in percutaneous coronary interventions of chronic total occluded lesions: a 2-year observational study
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/2522ee694d03434bbd57160c822b8aaa
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Risk Factors For Radiation-Induced Skin Ulceration in Percutaneous Coronary Interventions of Chronic Total Occluded Lesions: A 2-Year Observational Study

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