Symmetric spike timing-dependent plasticity at CA3–CA3 synapses optimizes storage and recall in autoassociative networks

STDP is dependent on the timing of pre- and post-synaptic activity. Here, the authors describe a symmetric STDP induction rule at CA3-CA3 synapses, which induces LTP over a broad range of paring intervals. Modelling suggests that this STDP rule may enhance storage capacity and pattern completion in...

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Autores principales:	Rajiv K. Mishra, Sooyun Kim, Segundo J. Guzman, Peter Jonas
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2528ec264add48ebb5b0b959f21c3687
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spelling	oai:doaj.org-article:2528ec264add48ebb5b0b959f21c36872021-12-02T16:57:02ZSymmetric spike timing-dependent plasticity at CA3–CA3 synapses optimizes storage and recall in autoassociative networks10.1038/ncomms115522041-1723https://doaj.org/article/2528ec264add48ebb5b0b959f21c36872016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11552https://doaj.org/toc/2041-1723STDP is dependent on the timing of pre- and post-synaptic activity. Here, the authors describe a symmetric STDP induction rule at CA3-CA3 synapses, which induces LTP over a broad range of paring intervals. Modelling suggests that this STDP rule may enhance storage capacity and pattern completion in the CA3 cell network.Rajiv K. MishraSooyun KimSegundo J. GuzmanPeter JonasNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Rajiv K. Mishra Sooyun Kim Segundo J. Guzman Peter Jonas Symmetric spike timing-dependent plasticity at CA3–CA3 synapses optimizes storage and recall in autoassociative networks
description	STDP is dependent on the timing of pre- and post-synaptic activity. Here, the authors describe a symmetric STDP induction rule at CA3-CA3 synapses, which induces LTP over a broad range of paring intervals. Modelling suggests that this STDP rule may enhance storage capacity and pattern completion in the CA3 cell network.
format	article
author	Rajiv K. Mishra Sooyun Kim Segundo J. Guzman Peter Jonas
author_facet	Rajiv K. Mishra Sooyun Kim Segundo J. Guzman Peter Jonas
author_sort	Rajiv K. Mishra
title	Symmetric spike timing-dependent plasticity at CA3–CA3 synapses optimizes storage and recall in autoassociative networks
title_short	Symmetric spike timing-dependent plasticity at CA3–CA3 synapses optimizes storage and recall in autoassociative networks
title_full	Symmetric spike timing-dependent plasticity at CA3–CA3 synapses optimizes storage and recall in autoassociative networks
title_fullStr	Symmetric spike timing-dependent plasticity at CA3–CA3 synapses optimizes storage and recall in autoassociative networks
title_full_unstemmed	Symmetric spike timing-dependent plasticity at CA3–CA3 synapses optimizes storage and recall in autoassociative networks
title_sort	symmetric spike timing-dependent plasticity at ca3–ca3 synapses optimizes storage and recall in autoassociative networks
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/2528ec264add48ebb5b0b959f21c3687
work_keys_str_mv	AT rajivkmishra symmetricspiketimingdependentplasticityatca3ca3synapsesoptimizesstorageandrecallinautoassociativenetworks AT sooyunkim symmetricspiketimingdependentplasticityatca3ca3synapsesoptimizesstorageandrecallinautoassociativenetworks AT segundojguzman symmetricspiketimingdependentplasticityatca3ca3synapsesoptimizesstorageandrecallinautoassociativenetworks AT peterjonas symmetricspiketimingdependentplasticityatca3ca3synapsesoptimizesstorageandrecallinautoassociativenetworks
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Symmetric spike timing-dependent plasticity at CA3–CA3 synapses optimizes storage and recall in autoassociative networks

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